Senior Director, Health Economics & Outcomes Research (HEOR)

Summary/Responsibilities:
- Lead development, execution, and communication of payer evidence strategies aligned with brand and Value & Access priorities for early-stage pipeline assets.
- Collaborate with Value & Access, Commercial, Medical Affairs, Clinical Development, Regulatory Affairs, and Patient Advocacy.
- Drive understanding of payer/HTA requirements for patient-relevant outcomes and health utility measurement.
- Assess and shape patient-relevant outcomes requirements for HTA/access to support differentiation and value demonstration.
- Ensure payer evidence requirements are incorporated into clinical development plans.
- Develop asset-specific patient-relevant outcomes strategies using disease conceptual models.
- Plan patient-relevant endpoints and oversee implementation in clinical trials.
- Lead early Joint Clinical Assessment (JCA) strategy, assessing access implications and market trade-offs.
- Identify payer evidence gaps and inform integrated evidence planning.
- Manage external partners for PRO development/validation, health state valuation (time trade-off/standard gamble), and patient preference research (as appropriate).
- Lead scientific interactions with HTA agencies (e.g., EU HTA JSC, NICE, CADTH), including briefing materials and evidence packages for PRO endpoints/MCIDs.
- Support regulatory and patient advocacy scientific interactions.
- In partnership with Integrated Evidence Teams (IET), analyze patient-relevant outcomes data to strengthen value propositions.
- Drive scientific communication (presentations/publications).
- Assess business development opportunities against payer/HTA requirements.

Qualifications:
- 12+ years pharma experience; 7+ years HEOR experience; at least 5 years patient-relevant outcomes research.
- Advanced degree in health economics/outcomes research/related field.
- Deep knowledge of market access, value, and global HTA frameworks.
- Proven experience developing/executing patient-relevant outcomes strategies.
- Experience evaluating/developing/validating PRO measures for regulatory/payer/HTA.
- Experience with HTA submissions/value dossiers/briefing books.
- Ability to influence senior cross-functional stakeholders and lead multiple complex initiatives.
- Recognized PRO leader with external visibility.
- Experience engaging HTA agencies/payers/health economists/clinical experts/patient advocacy.
- Rare disease experience preferred.
- People leadership experience preferred.