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Senior Director, Global Medical Affairs

Centessa Pharmaceuticals
September 09, 2026
Full-time
Remote
Worldwide
Medical Affairs
Role: Senior Director, Global Medical Affairs for Centessa's orexin receptor 2 agonist (cleminorexton) program, leading strategic medical initiatives across the product lifecycle, including launch readiness, scientific leadership, and evidence generation. Responsibilities: develop and execute global medical strategies; serve as core member of cross-functional asset team; oversee scientific engagement with KOLs, investigators, and societies; collaborate with commercial, regulatory, and clinical teams for integrated launch and lifecycle planning; provide medical guidance for external scientific materials and publications. Requirements: MD, PharmD, or PhD; 10+ years in Medical Affairs with 5+ years global experience; demonstrated success leading product launches, preferably in neuroscience, sleep medicine, neurology, or psychiatry; experience as a global medical lead for late-stage or marketed products; strong understanding of evidence generation, payer needs, and commercialization. HighValue: neuroscience, sleep disorders, narcolepsy, rare diseases, global product launch, evidence generation, external scientific engagement, cross-functional collaboration. WorkSetup: remote US-based with ~20% travel.