Senior Director, Financial Planning & Analysis - Commercial

Senior Director of Commercial Finance

Responsibilities
- Serve as the finance business partner to the US Commercial Vice President and Business Unit Lead, leading strategic decision support and shaping long-term commercial strategy and execution.
- Influence senior executives across Commercial, Medical, Human Resources, Global Finance, and Corporate functions to align financial plans with enterprise goals.
- Anticipate market, competitive, and regulatory dynamics and provide actionable insights that guide commercial strategy and resource allocation.
- Lead the annual budget, long-range planning process, and monthly forecasting cycles for the US Commercial BU, ensuring integration with global planning frameworks.
- Oversee US revenue and operating expense management; drive analytical rigor and scenario planning to support portfolio optimization and launch readiness.
- Identify value drivers and enterprise risks; develop innovative, data-driven solutions to enable profitable and sustainable growth.
- Lead and develop a high-performing team aligned with Vertex leadership behaviors and culture.
- Build a culture of accountability, operational excellence, and continuous improvement.
- Partner with HR on workforce planning and organizational design to support growth of the US Commercial business.
- Partner with Global Commercial Finance, Accounting, Tax, and Investor Relations to strengthen financial systems, processes, and communication.
- Drive alignment during key business cycles to ensure readiness for launches, lifecycle management, and competitive/market shifts.
- Represent US Commercial Finance in enterprise forums with strategic, data-driven perspectives.

Qualifications / Required Skills
- Bachelor’s degree in Finance, Accounting, or a related field (required).
- 15+ years of progressive finance experience in commercial, FP&A, or strategic roles, including experience supporting senior executives (or equivalent combination of education and experience).
- Demonstrated success leading financial strategy in a complex and highly regulated environment.
- Extensive experience in drug development, commercialization, launch planning, pricing, reimbursement, and US market access.
- Proven ability to influence executives and lead enterprise-level initiatives.

Preferred Skills
- MBA or other advanced degree (strongly preferred).
- Expertise with Excel and PowerPoint; working knowledge of Hyperion or similar planning tools.

Skills
- Expert financial modeling, valuation, analytics, and scenario planning.
- Strategic thinker able to translate complex information into useful insights for senior leaders.
- Exceptional executive communication and presentation skills.
- Ability to lead through ambiguity, drive organizational change, and innovate in a fast-paced environment.
- Deep business acumen and understanding of the biotechnology market and commercial strategy.
- Demonstrated ability to lead teams and foster an inclusive, development-oriented culture.

Benefits / Compensation (as stated)
- Pay range: $212,000 - $318,000.
- Eligible for an annual bonus and annual equity awards.

Application instructions
- Contact Talent Acquisition at ApplicationAssistance@vrtx.com for hiring-process accommodations.