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Senior Director, Clinical Practice Liaisons

Madrigal Pharmaceuticals
Full-time
Remote friendly (Los Angeles, CA)
United States
$262,000 - $320,000 USD yearly
Medical Affairs

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Role Summary

The Senior Director, Clinical Practice Liaison (CPL) is a field-based leadership role responsible for the strategic and tactical oversight of the CPL team within a defined U.S. region. This position manages CPL development, ensures alignment with the medical strategy, regulatory compliance, and delivers scientific value to internal and external stakeholders. Interfaces regularly with cross-functional teams and external partners to execute medical objectives and support lifecycle activities.

Responsibilities

  • Team Leadership & Development: Recruit, coach, and manage performance of regional CPLs; foster continuous development through mentoring and training; align CPL activities with strategic objectives and tactical plans.
  • Medical Strategy Execution: Drive implementation of regional field medical strategies; translate national objectives into regionally tailored activities; partner with cross-functional teams to integrate field insights into medical planning.
  • Cross-functional Collaboration: Collaborate with Sales, Marketing, Market Access, and Clinical Operations; serve as a field-based liaison for HQ Medical Affairs initiatives; contribute to launch readiness and lifecycle management strategies.
  • Clinical Trial Support: Collaborate with Clinical Operations to ensure successful study execution based on recognized needs.
  • Congress & External Engagement: Represent Medical Affairs at U.S. medical congresses in a compliant manner; coordinate booth planning, scientific exchange, competitive intelligence, and post-conference debriefs.
  • Strategic Team Building: Contribute to the design and structure of the U.S. Field Medical team; identify evolving business needs and adjust regional capabilities accordingly.
  • Compliance & Quality: Ensure all CPL activities comply with SOPs, industry standards, and regulations; uphold the highest ethical standards in external engagements.
  • Travel Requirement: Willingness to travel 25–75% for congresses, site visits, and stakeholder engagement.

Qualifications

  • Advanced degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, etc.).
  • Minimum 5 years of Medical Affairs experience, including at least 3 years as an MSL or equivalent (translatable clinical practice experience considered).
  • Minimum 3 years of people management experience or formal leadership development participation.
  • In-depth knowledge of clinical medicine and medical research; experience in cardiometabolic health or MASH/NASH preferred.
  • Proven ability to understand, communicate, and translate complex scientific information.
  • Strong knowledge of the U.S. healthcare system, FDA regulations, and medical affairs compliance standards.
  • Demonstrated cross-functional collaboration, project execution, and strategic planning skills.
  • Proficiency in Microsoft Office, virtual platforms (e.g., Zoom), and CRM systems (e.g., Veeva).

Preferred Attributes

  • Strong interpersonal, presentation, and relationship-building skills.
  • Adaptable and proactive in a fast-paced, evolving environment.
  • Passion for mentoring, team building, and field-based medical innovation.

Education

  • Advanced degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, etc.).
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