Senior Director, Clinical Development
PTC Therapeutics, Inc.
September 04, 2026
Remote friendly (New Jersey, United States)
United States
Clinical Research and Development
Job Description Summary: Senior Director, Clinical Development provides strategic input for clinical/medical aspects of all phases of drug development and works with R&D leadership to achieve clinical development goals.
Primary Duties/Responsibilities:
- Lead/contribute to global clinical development strategy for assigned indication/therapeutic area.
- Lead design of Clinical Development Plans (CDPs) and ensure they demonstrate clinical/medical benefit and meet compound/commercial objectives; provide clinical input to non-clinical and commercial functions.
- Manage external partners (e.g., CROs/vendors/consultants/collaborators); monitor budgets; review/approve contracts, work orders, and invoices; assess partners as needed.
- Medically responsible for clinical studies; lead analysis of study results and documentation of outcomes.
- Facilitate cross-functional communication with internal groups and external stakeholders (e.g., collaborators, KOLs, investigators, regulatory authorities).
- Ensure compliance with GCP and relevant regulatory/SOP requirements.
- Represent Clinical Development in external meetings; may author/review clinical/medical materials for external audiences.
- Support assessment of in-licensing candidates as needed.
- May manage, coach, and mentor direct reports; perform other assigned tasks.
Qualifications/Skills:
- MD required; 5+ years clinical drug development experience in pharma/biotech.
- Hands-on experience leading large, multi-country clinical programs.
- Working knowledge of early/late-phase development and regulatory processes.
- Ability to lead/oversee clinical trial design, conduct, and interpretation.
- Experience developing regulatory submissions; ability to influence without authority.
- Proficiency with Microsoft Office; excellent verbal/written communication.
- Independent, collaborative work in a matrix environment; strong analytical/problem-solving and planning skills.
- Travel domestically/internationally (up to 30%).
Preferred:
- Board certification/equivalent; experience in rare/orphan disease; previous supervisory experience.
Compensation/Benefits (if eligible):
- Expected base salary range: $289,200–$364,000; plus short- and long-term incentives and medical/dental/vision and retirement savings plans.
Primary Duties/Responsibilities:
- Lead/contribute to global clinical development strategy for assigned indication/therapeutic area.
- Lead design of Clinical Development Plans (CDPs) and ensure they demonstrate clinical/medical benefit and meet compound/commercial objectives; provide clinical input to non-clinical and commercial functions.
- Manage external partners (e.g., CROs/vendors/consultants/collaborators); monitor budgets; review/approve contracts, work orders, and invoices; assess partners as needed.
- Medically responsible for clinical studies; lead analysis of study results and documentation of outcomes.
- Facilitate cross-functional communication with internal groups and external stakeholders (e.g., collaborators, KOLs, investigators, regulatory authorities).
- Ensure compliance with GCP and relevant regulatory/SOP requirements.
- Represent Clinical Development in external meetings; may author/review clinical/medical materials for external audiences.
- Support assessment of in-licensing candidates as needed.
- May manage, coach, and mentor direct reports; perform other assigned tasks.
Qualifications/Skills:
- MD required; 5+ years clinical drug development experience in pharma/biotech.
- Hands-on experience leading large, multi-country clinical programs.
- Working knowledge of early/late-phase development and regulatory processes.
- Ability to lead/oversee clinical trial design, conduct, and interpretation.
- Experience developing regulatory submissions; ability to influence without authority.
- Proficiency with Microsoft Office; excellent verbal/written communication.
- Independent, collaborative work in a matrix environment; strong analytical/problem-solving and planning skills.
- Travel domestically/internationally (up to 30%).
Preferred:
- Board certification/equivalent; experience in rare/orphan disease; previous supervisory experience.
Compensation/Benefits (if eligible):
- Expected base salary range: $289,200–$364,000; plus short- and long-term incentives and medical/dental/vision and retirement savings plans.