Senior Biologist
Eli Lilly and Company
September 02, 2026
On-site
Indianapolis, IN
Clinical Research and Development
Responsibilities:
- Support the development, optimization, and implementation of assays to assess biological activity of therapeutic proteins, peptides, and new modalities (including gene and cell therapies) in the laboratory.
- Support transfer of potency assays for QC release and stability testing to meet product and regulatory requirements.
- Execute experiments; review/analyze data; author technical documents; contribute to regulatory submission sections.
- Support bioassay lab operations (cell culturing, reagent acquisition/qualification, instrument purchase/qualification).
- Coordinate/collaborate with internal and external partners as part of cross-functional teams.
- Evaluate and assess emerging technologies suitable for bioassay development.
Basic Requirements:
- MS in Molecular Biology, Immunology, Biochemistry, Bioanalytical Chemistry (0–2 years pharma/biotech) OR BS in those fields (2–3 years pharma/biotech).
- Hands-on potency assay experience (binding: ELISA/SPR and/or cell-based: luciferase reporter assays).
- Mammalian cell culture proficiency (adherent/suspension maintenance, passaging, cryopreservation).
- Experience with engineered cell lines (stable reporter, knockout/knock-in).
- Strong interpersonal/communication skills; cross-functional collaboration.
- Ability to prioritize/manage workload in a fast-paced, deadline-driven environment.
- Work authorization required in the US; no visa sponsorship.
Additional Skills/Preferences:
- Genome editing (CRISPR-Cas9, HDR, NHEJ) including design, execution, and confirmation.
- Core molecular biology (PCR, qPCR, gels, cloning, plasmid prep, sequencing).
- GMP quality systems; FDA/EMA regulations for potency assay development.
- Statistical analysis tools (SoftMax Pro, PLA 2.0, JMP/SAS).
Location/Work model:
- Onsite at Lilly’s Tech Center North campus, Indianapolis, IN.
- Support the development, optimization, and implementation of assays to assess biological activity of therapeutic proteins, peptides, and new modalities (including gene and cell therapies) in the laboratory.
- Support transfer of potency assays for QC release and stability testing to meet product and regulatory requirements.
- Execute experiments; review/analyze data; author technical documents; contribute to regulatory submission sections.
- Support bioassay lab operations (cell culturing, reagent acquisition/qualification, instrument purchase/qualification).
- Coordinate/collaborate with internal and external partners as part of cross-functional teams.
- Evaluate and assess emerging technologies suitable for bioassay development.
Basic Requirements:
- MS in Molecular Biology, Immunology, Biochemistry, Bioanalytical Chemistry (0–2 years pharma/biotech) OR BS in those fields (2–3 years pharma/biotech).
- Hands-on potency assay experience (binding: ELISA/SPR and/or cell-based: luciferase reporter assays).
- Mammalian cell culture proficiency (adherent/suspension maintenance, passaging, cryopreservation).
- Experience with engineered cell lines (stable reporter, knockout/knock-in).
- Strong interpersonal/communication skills; cross-functional collaboration.
- Ability to prioritize/manage workload in a fast-paced, deadline-driven environment.
- Work authorization required in the US; no visa sponsorship.
Additional Skills/Preferences:
- Genome editing (CRISPR-Cas9, HDR, NHEJ) including design, execution, and confirmation.
- Core molecular biology (PCR, qPCR, gels, cloning, plasmid prep, sequencing).
- GMP quality systems; FDA/EMA regulations for potency assay development.
- Statistical analysis tools (SoftMax Pro, PLA 2.0, JMP/SAS).
Location/Work model:
- Onsite at Lilly’s Tech Center North campus, Indianapolis, IN.