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Senior Associate Scientist, Bioinformatics

Alnylam Pharmaceuticals
Full-time
Remote friendly (Cambridge, MA)
United States
$76,300 - $114,500 USD yearly
Clinical Research and Development

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Role Summary

Senior Associate Scientist, Bioinformatics. Role focuses on analyzing and communicating results from large NGS datasets, developing and evaluating sequencing pipelines, and contributing to a bioinformatics team within a RNAi therapeutics company.

Responsibilities

  • Run and develop proprietary Next Generation Sequencing analysis pipelines for short- and long-read technologies.
  • Communicate results of computational analyses to interdisciplinary teams of scientists.
  • Investigate state-of-the-art statistical methods and omics tools for novel sequencing technologies (e.g., RNA modification measures, proteogenomics).
  • Assist in the interpretation of results from complex scientific experiments.
  • Professionally maintain code in a version-controlled repository.
  • Contribute to our data science culture.

Qualifications

  • M.S. in a quantitative discipline, or B.S. with 2+ years of equivalent professional experience.
  • Coding capability in R and Python.
  • Prior experience with the analysis of omics-based biological datasets; familiarity with NGS and differential expression analysis tools preferred.
  • Experience with statistical methods and comfort reading and understanding scientific publications is preferred.
  • Drive to learn and understand new sequencing-based technologies, and to develop and troubleshoot downstream analysis pipelines.
  • Comfort working with Unix systems and cloud-based computing environments and tools (e.g., AWS, Docker).
  • Knowledge of, or interest in learning, the fundamentals of RNAi biology.
  • Experience communicating and presenting scientific results, and collaborating with colleagues with varied skill sets.

Skills

  • Bioinformatics analysis
  • NGS data processing
  • Statistical methods
  • Programming in R and Python
  • Version control and collaboration

Education

  • M.S. in a quantitative discipline, or B.S. with relevant experience as listed in Qualifications
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