Scientist, Pharmacokinetics
Merck
September 02, 2026
Remote friendly (West Point, PA)
United States
Clinical Research and Development
Responsibilities:
- Support drug discovery and development by executing in vitro ADME/DMPK assays and generating high-quality quantitative bioanalytical data.
- Conduct experiments characterizing drug metabolism and disposition (with strong emphasis on LC-MS–based bioanalysis) and contribute data to inform project decisions.
- Perform laboratory work with technical rigor, reproducibility, and data quality; troubleshoot assays and workflows.
- Collaborate with multidisciplinary teams; apply LC-MS technologies and emerging automation tools; optimize assay execution and workflows.
Qualifications:
- Education: Bachelor’s degree with 1–3 years relevant experience, or Master’s degree with 0–2 years in analytical chemistry, biochemistry, pharmaceutical sciences, or related.
Required Experience/Skills:
- Strong foundation in analytical chemistry/biochemistry.
- Hands-on LC-MS/MS quantitative bioanalysis for small molecules or biologics (sample prep, method execution, data acquisition).
- Familiarity with biological matrices (e.g., plasma, tissues, enzymes, cell systems).
- Proficiency with data tools (Excel, GraphPad Prism, electronic lab notebooks).
- Attention to detail; generating high-quality, reproducible data.
- Follow protocols and troubleshoot experimental/instrumentation issues.
- Communication and collaboration; problem-solving, learning agility, growth mindset.
Preferred Experience/Skills:
- In vitro ADME/DMPK assays (metabolic stability, protein binding, reaction phenotyping, enzyme inhibition).
- LC-MS instrumentation knowledge (troubleshooting, maintenance, method optimization).
- Cell/tissue or subcellular systems; lab automation/liquid handling/high-throughput workflows; Spotfire.
- Prior pharma/biotech/CRO experience.
Benefits:
- Eligible for annual bonus and long-term incentive (if applicable).
- Comprehensive benefits including medical, dental, vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days.
Application:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub for current employees). Application deadline is listed on the posting.
- Support drug discovery and development by executing in vitro ADME/DMPK assays and generating high-quality quantitative bioanalytical data.
- Conduct experiments characterizing drug metabolism and disposition (with strong emphasis on LC-MS–based bioanalysis) and contribute data to inform project decisions.
- Perform laboratory work with technical rigor, reproducibility, and data quality; troubleshoot assays and workflows.
- Collaborate with multidisciplinary teams; apply LC-MS technologies and emerging automation tools; optimize assay execution and workflows.
Qualifications:
- Education: Bachelor’s degree with 1–3 years relevant experience, or Master’s degree with 0–2 years in analytical chemistry, biochemistry, pharmaceutical sciences, or related.
Required Experience/Skills:
- Strong foundation in analytical chemistry/biochemistry.
- Hands-on LC-MS/MS quantitative bioanalysis for small molecules or biologics (sample prep, method execution, data acquisition).
- Familiarity with biological matrices (e.g., plasma, tissues, enzymes, cell systems).
- Proficiency with data tools (Excel, GraphPad Prism, electronic lab notebooks).
- Attention to detail; generating high-quality, reproducible data.
- Follow protocols and troubleshoot experimental/instrumentation issues.
- Communication and collaboration; problem-solving, learning agility, growth mindset.
Preferred Experience/Skills:
- In vitro ADME/DMPK assays (metabolic stability, protein binding, reaction phenotyping, enzyme inhibition).
- LC-MS instrumentation knowledge (troubleshooting, maintenance, method optimization).
- Cell/tissue or subcellular systems; lab automation/liquid handling/high-throughput workflows; Spotfire.
- Prior pharma/biotech/CRO experience.
Benefits:
- Eligible for annual bonus and long-term incentive (if applicable).
- Comprehensive benefits including medical, dental, vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days.
Application:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub for current employees). Application deadline is listed on the posting.