Scientist - Medicinal Chemistry

Role Summary

Scientist in Medicinal Chemistry. This onsite laboratory role focuses on the design, synthesis, and purification of novel compounds for potential clinical drug development. You may contribute to Amgen’s Induced Proximity Platform (IPP), which applies PROTAC modalities to modulate challenging targets. This position is based at the Thousand Oaks site.

Responsibilities

• The Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry.
• Furthermore, you will contribute to the design of new compounds and the development of structure-activity relationships.
• This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques.
• They will be recognized as a lab leader and should demonstrate excellent verbal and written communication skills.
• Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications.

Qualifications

• Required: Doctorate Degree
• Required: Master’s degree and 2 years of laboratory experience, or Bachelor’s degree and 4 years of laboratory experience
• Preferred: Track record of accomplishments (e.g., peer-reviewed publications)
• Preferred: Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
• Preferred: Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
• Preferred: Demonstration of good lab practices, with particular attention to safety
• Preferred: Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams