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Scientist

GSK
Full-time
On-site
Collegeville, PA
Clinical Research and Development

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Role Summary

Scientist to join the iPSC Systems team within the Human Biology - Target Discovery department at GSK's Upper Providence facility. Lab-based role focused on advancing iPSC-derived translational models for neurodegenerative diseases, with emphasis on model development, assay refinement, and data analysis. On-site position with required presence at the Upper Providence location.

Responsibilities

  • Develop physiological and disease-relevant cellular models and refine assays to achieve research objectives.
  • Communicate experimental findings effectively, both in writing and verbally, to stakeholders.
  • Ensure compliance with all R&D integrity practices, ethical codes, standards, and safety protocols.
  • Collaborate in a matrix team environment, contributing to high scientific standards and project success.

Qualifications

  • Required: Bachelor's or master's degree in Biochemistry, Molecular and Cellular Biology, Neuroscience, or related field, with 3–5 years of experience in iPSC-model development.
  • Required: Expertise in iPSC culture and differentiation.
  • Required: Experience in genetic, proteomic, imaging, and other omics technologies analytical pipelines.
  • Required: Experience in neurodegenerative diseases.
  • Required: Ability to independently analyze, summarize, and interpret experimental data, with meticulous record-keeping.
  • Preferred: Experience programming and operating automated liquid handling systems.
  • Preferred: Strong relationship-building, adaptable thinking, and troubleshooting skills.
  • Preferred: Experience conducting perturbation studies using tool compounds and gene editing techniques, preferably CRISPRn/i/a.

Skills

  • iPSC culture and differentiation
  • Data analysis and interpretation
  • Molecular biology techniques
  • Automated liquid handling systems (preferred)

Education

  • Bachelor's or master's degree in Biochemistry, Molecular and Cellular Biology, Neuroscience, or related field

Additional Requirements

  • On-site, lab-based work at Upper Providence, USA
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