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Role Summary
Research Scientist & Cell Assay Specialist
Responsibilities
- Maintains cell line cultures (growth, extraction of specimens)
- Prepares specimens for analysis; aliquots, transports and distributes specimens
- Maintains tracking information for specimens
- Coordinates prioritization, receipt and delivery of laboratory specimens
- Verifies accurate documentation relative to specimen processing
- Accepts or rejects specimens according to established standards and performs specimen investigation procedures to resolve lab specimen issues or problems
- Runs RNA and protein assays with necessary troubleshooting
- Demonstrates an understanding of the theory and scientific principles of laboratory testing as well as the technical, procedural and problem-solving aspects
- Performs and interprets tests at all complexity levels
- Correlates abnormal laboratory data with pathological states, determines the validity of test results and the need for additional tests
- Determines the validity of test results through the monitoring and/or verifying of quality controls, standards, etc
- Communicates test results, reference ranges, specimen requirements, and other pertinent information to authorized sources
- Assumes responsibility for good documentation practices and maintains clear and legible records
- Accumulates data from analyses, prepares charts, graphs, statistical tables for presentation to Research Staff Supervisor for final analysis
- The successful candidate will assist with general lab duties, protocols and compliance responsibilities, and will be proactively involved in assigned research
- Maintains instrumentation and equipment along with its cleanliness
- Performs preventive maintenance and record keeping procedures
- Maintains appropriate workstation supplies and inventory
- Develops and designs multiple assays for screening in-vitro and in-vivo biological targets
- Collects and interprets data for biomarker and biological characterization assays including cell-based, multiplexed protein assays, polymerase chain reaction and flow cytometry methods
- Develops biochemical assays for lead validation and optimization for disease-related targets to predict outcome in supporting development by enabling earlier decision making, reducing investment risk and avoiding late phase failures
- Emphasis may be development of biochemical assays for high throughput screening. May oversee screening operations, including scheduling, assay performance and data flow
- May work with manufacturing and quality control to develop tests, as well as analyze and report results
- Prepares technical reports, summaries, protocols and quantitative analyses
Qualifications
- Bachelor’s degree in chemical, physical, biological or clinical laboratory science or medical technology preferred; Master's degree preferred
- Minimum of two years of progressive lab experience (independent/leading role preferred); 5+ years preferred
- Typical physical demands include visual acuity and the ability to distinguish colors; manual dexterity to handle specimens diagnose/troubleshoot equipment; may require extended periods of sitting, standing and walking, light lifting may be required
Skills
- Laboratory techniques and assay development
- Data analysis and interpretation
- Documentation and reporting
- Quality control and compliance
- Team collaboration and communication
Education
- Bachelor’s degree required (specific science discipline as listed above); Master’s degree preferred
Additional Requirements
- Must be able to perform the essential functions of the position, with or without reasonable accommodation