Program Manager - Technical Operations
Neurocrine Biosciences
September 03, 2026
Remote friendly (San Diego, CA)
United States
Operations
About The Role
The Program Manager, Technical Operations supports planning, execution, and operational effectiveness of Technical Operations programs across the development portfolio, providing program management leadership for complex, multidisciplinary initiatives.
Your Contributions
Program and Project Management
- Lead integrated planning and execution of Technical Operations/CMC programs and major workstreams from development planning through key milestones
- Develop and communicate integrated plans, timelines, milestones, critical paths, dependencies, decision points, and deliverables
- Establish meeting cadences, governance forums, decision logs, action trackers, and status reporting
- Monitor execution; proactively identify schedule risks, resource constraints, dependencies, and emerging issues
- Partner with SME functional leaders to evaluate options and develop mitigation/escalation strategies
- Facilitate scenario planning and trade-off discussions
- Maintain documentation of assumptions, decisions, risks, actions, and accountabilities
CMC and Technical Operations Integration
- Integrate plans across CMC disciplines (API/drug substance, analytical, drug product/pharmaceutical, manufacturing, supply chain, quality, regulatory)
- Connect upstream/downstream impacts and coordinate program-level milestones and readiness plans
Strategic and Operational Support
- Translate strategic objectives into tactical plans, deliverables, timelines, and ownership
- Provide leadership visibility into progress, risks, constraints, decisions, and operational considerations
Risk, Issue, and Decision Management
- Identify, assess, track, and communicate risks/issues; develop mitigations and contingencies
- Ensure decisions are data-supported, documented, and incorporated into updated plans; escalate as needed
Operational Excellence
- Improve program management processes/workflows/governance and cross-functional collaboration
Requirements
- 6+ years applicable experience + Bachelor’s OR 4+ years + Master’s OR 2+ years + PharmD/PhD
- Direct experience supporting CMC, Technical Operations, or manufacturing (required)
- Strong working knowledge of pharmaceutical development and CMC/Technical Operations across the product lifecycle
- Working knowledge of core CMC disciplines listed above
- Ability to integrate plans, milestones, dependencies, risks, and deliverables across multiple disciplines/workstreams
- Knowledge of governance, risk/decision/escalation practices; strong cross-functional influencing and communication skills
- Strong planning/organizational skills; continuous-improvement mindset
Benefits (explicitly stated)
- Retirement savings plan (company match), paid vacation/holidays/personal days, caregiver/parental and medical leave, and medical/prescription drug/dental/vision coverage
Compensation (explicitly stated)
- Annual base salary: $130,800.00-$179,000.00; annual bonus target 30%; equity long-term incentive eligibility
The Program Manager, Technical Operations supports planning, execution, and operational effectiveness of Technical Operations programs across the development portfolio, providing program management leadership for complex, multidisciplinary initiatives.
Your Contributions
Program and Project Management
- Lead integrated planning and execution of Technical Operations/CMC programs and major workstreams from development planning through key milestones
- Develop and communicate integrated plans, timelines, milestones, critical paths, dependencies, decision points, and deliverables
- Establish meeting cadences, governance forums, decision logs, action trackers, and status reporting
- Monitor execution; proactively identify schedule risks, resource constraints, dependencies, and emerging issues
- Partner with SME functional leaders to evaluate options and develop mitigation/escalation strategies
- Facilitate scenario planning and trade-off discussions
- Maintain documentation of assumptions, decisions, risks, actions, and accountabilities
CMC and Technical Operations Integration
- Integrate plans across CMC disciplines (API/drug substance, analytical, drug product/pharmaceutical, manufacturing, supply chain, quality, regulatory)
- Connect upstream/downstream impacts and coordinate program-level milestones and readiness plans
Strategic and Operational Support
- Translate strategic objectives into tactical plans, deliverables, timelines, and ownership
- Provide leadership visibility into progress, risks, constraints, decisions, and operational considerations
Risk, Issue, and Decision Management
- Identify, assess, track, and communicate risks/issues; develop mitigations and contingencies
- Ensure decisions are data-supported, documented, and incorporated into updated plans; escalate as needed
Operational Excellence
- Improve program management processes/workflows/governance and cross-functional collaboration
Requirements
- 6+ years applicable experience + Bachelor’s OR 4+ years + Master’s OR 2+ years + PharmD/PhD
- Direct experience supporting CMC, Technical Operations, or manufacturing (required)
- Strong working knowledge of pharmaceutical development and CMC/Technical Operations across the product lifecycle
- Working knowledge of core CMC disciplines listed above
- Ability to integrate plans, milestones, dependencies, risks, and deliverables across multiple disciplines/workstreams
- Knowledge of governance, risk/decision/escalation practices; strong cross-functional influencing and communication skills
- Strong planning/organizational skills; continuous-improvement mindset
Benefits (explicitly stated)
- Retirement savings plan (company match), paid vacation/holidays/personal days, caregiver/parental and medical leave, and medical/prescription drug/dental/vision coverage
Compensation (explicitly stated)
- Annual base salary: $130,800.00-$179,000.00; annual bonus target 30%; equity long-term incentive eligibility