Process Development Senior Principal Scientist Bioconjugates

Role: Process Development Senior Principal Scientist specializing in bioconjugates at Amgen, focusing on antibody drug conjugates (ADCs). Objectives include leading development of sustainable, cost-effective manufacturing processes for clinical-stage bioconjugates, driving technology innovation, supporting cGMP manufacturing, and facilitating regulatory submissions. Responsibilities encompass leading multidisciplinary teams, advancing process understanding through modeling and characterization, and ensuring successful technology transfer. Requirements include a PhD, PharmD, or MD with 3+ years (or relevant experience for other degrees), with preferred expertise in ADC bioconjugation, GMP manufacturing, and tech transfer. The role demands demonstrated leadership, publication record, and experience in bioconjugation process development, especially with HPAPI linkers/payloads. High-value biopharma specifics: focus on ADCs, bioconjugation, process development, GMP compliance, and regulatory support. Located at Amgen’s Thousand Oaks, California campus, the role may involve cross-functional collaboration. The position emphasizes innovation, leadership, and technical expertise in bioconjugate manufacturing for late-stage clinical development.