Principal Quantitative Pharmacologist

Role: Principal Quantitative Pharmacologist in Pharmacometrics supporting drug development programs. Main objectives include designing, conducting, and communicating sophisticated PMx analyses to inform development strategies, regulatory interactions, and potential program modifications. Responsibilities encompass authoring contributions for regulatory documents (IBs, briefing books), supporting pre-IND and other HA meetings, preparing study reports, and mentoring staff. The role also involves representing PMx at key regulatory interactions and providing strategic insights for clinical development. Requirements include a PhD with 5+ years or an MS with relevant industry experience, expertise in pharmacokinetics, pharmacology, non-compartmental analysis, and familiarity with modeling approaches such as exposure-response, Bayesian methods, and disease modeling. Preferred skills include translational modeling and QSP. The position is based in Tarrytown, NY, with a flexible work model (4 days onsite) and involves some regulatory and scientific cross-team collaboration. The role is senior-level, emphasizing independent analysis, regulatory document authoring, and stakeholder communication within biopharma development phases, particularly for biologics or small molecules in early to late clinical stages.