Principal Program Manager – Engineering Projects
ImmunityBio, Inc.
August 26, 2026
On-site
Dunkirk, NY
IT
Position Summary:
The Principal Program Manager, Engineering Projects leads a portfolio of complex capital, facility, utility, equipment, and technical-infrastructure programs enabling ImmunityBio’s clinical and commercial GMP manufacturing operations. Provides strategic program leadership from concept/capital approval through design, construction, commissioning, qualification, operational handover, and closeout. Ensures delivery safely, compliantly, on schedule, within approved budgets, and aligned with business, quality, and regulatory requirements.
Responsibilities:
- Lead GMP capital/facility/utility/equipment/technical-infrastructure programs from concept/business case through construction, CQV, turnover, and closeout.
- Set program strategy, roadmap, governance, decision cadence, priorities, resources, and performance measures.
- Maintain integrated project controls (scope, WBS, schedule, critical path, cost forecast, cash flow, risks, dependencies, change impacts).
- Lead cross-functional delivery across Engineering, Facilities, Manufacturing, Quality, Validation, EHS, Supply Chain, Finance, Procurement, and external engineering/construction/CQV partners.
- Integrate GMP/Quality/CQV requirements (design qualification as applicable, commissioning, IQ/OQ/PQ, documentation review, change control dependencies, readiness for release).
- Provide executive reporting/briefs, scenario analyses, risk escalations, and recommendations.
- Direct capital planning/financial controls (business cases, budget baselines, forecasting, invoice/vendor performance, change-order governance).
- Establish scalable PM standards/tools/dashboards/SOPs/templates; drive lessons learned.
- Define closeout/operational handover requirements; ensure completeness/acceptance.
- Ensure integration with quality-system processes (change control, quality risk management, CAPA/deviations, document control, inspection readiness).
- Coach/mentor project managers; support internal/external audits/inspections.
- Perform ad-hoc duties/projects as assigned.
Qualifications:
- Bachelor’s degree in engineering, science, or relevant field required.
- 10+ years progressively responsible experience leading engineering/facilities/manufacturing/validation/capital projects; at least 6 years managing complex GMP-regulated manufacturing.
- Experience delivering capital projects through design, construction, commissioning, qualification, operational handover, and closeout (scope/schedule/budget/risk/contractor coordination/change control).
- Facility buildouts and equipment CQV strongly preferred.
- Capital/infrastructure projects involving construction, utilities, and equipment installation in cGMP or similarly regulated environments preferred.
- Cross-functional and matrixed organization experience with external partners preferred.
- PMP or other project management certification preferred.
Skills & Abilities:
- Executive presence, strategic judgment, influence without authority, conflict resolution.
- Knowledge of stage-gate, predictive, and hybrid delivery methodologies for regulated environments.
- Exceptional written/verbal/presentation skills across technical and executive audiences.
- Strong meeting facilitation, cross-functional communication, and stakeholder alignment.
- Strategic thinking; manage multiple priorities while ensuring detail/compliance.
- Understanding of facility/utility systems’ impact on GMP operations.
- Working knowledge of commissioning/validation and IQ/OQ/PQ development/execution.
- Proficiency with project management tools and MS Office; CAD/BIM familiarity a plus.
Working Environment:
- On-site as noted in the offer letter; Monday–Friday during standard business hours (flexibility with manager approval).
- Mobility required for office and construction/plant environments; lift/carry up to 20 lbs.
Benefits/Compensation (explicitly stated):
- Discretionary bonus and equity award.
- Annual base pay range: $148,500–$165,000.
Application Instructions:
- Application window anticipated to close 60 days from posting (or sooner if filled/closed).
The Principal Program Manager, Engineering Projects leads a portfolio of complex capital, facility, utility, equipment, and technical-infrastructure programs enabling ImmunityBio’s clinical and commercial GMP manufacturing operations. Provides strategic program leadership from concept/capital approval through design, construction, commissioning, qualification, operational handover, and closeout. Ensures delivery safely, compliantly, on schedule, within approved budgets, and aligned with business, quality, and regulatory requirements.
Responsibilities:
- Lead GMP capital/facility/utility/equipment/technical-infrastructure programs from concept/business case through construction, CQV, turnover, and closeout.
- Set program strategy, roadmap, governance, decision cadence, priorities, resources, and performance measures.
- Maintain integrated project controls (scope, WBS, schedule, critical path, cost forecast, cash flow, risks, dependencies, change impacts).
- Lead cross-functional delivery across Engineering, Facilities, Manufacturing, Quality, Validation, EHS, Supply Chain, Finance, Procurement, and external engineering/construction/CQV partners.
- Integrate GMP/Quality/CQV requirements (design qualification as applicable, commissioning, IQ/OQ/PQ, documentation review, change control dependencies, readiness for release).
- Provide executive reporting/briefs, scenario analyses, risk escalations, and recommendations.
- Direct capital planning/financial controls (business cases, budget baselines, forecasting, invoice/vendor performance, change-order governance).
- Establish scalable PM standards/tools/dashboards/SOPs/templates; drive lessons learned.
- Define closeout/operational handover requirements; ensure completeness/acceptance.
- Ensure integration with quality-system processes (change control, quality risk management, CAPA/deviations, document control, inspection readiness).
- Coach/mentor project managers; support internal/external audits/inspections.
- Perform ad-hoc duties/projects as assigned.
Qualifications:
- Bachelor’s degree in engineering, science, or relevant field required.
- 10+ years progressively responsible experience leading engineering/facilities/manufacturing/validation/capital projects; at least 6 years managing complex GMP-regulated manufacturing.
- Experience delivering capital projects through design, construction, commissioning, qualification, operational handover, and closeout (scope/schedule/budget/risk/contractor coordination/change control).
- Facility buildouts and equipment CQV strongly preferred.
- Capital/infrastructure projects involving construction, utilities, and equipment installation in cGMP or similarly regulated environments preferred.
- Cross-functional and matrixed organization experience with external partners preferred.
- PMP or other project management certification preferred.
Skills & Abilities:
- Executive presence, strategic judgment, influence without authority, conflict resolution.
- Knowledge of stage-gate, predictive, and hybrid delivery methodologies for regulated environments.
- Exceptional written/verbal/presentation skills across technical and executive audiences.
- Strong meeting facilitation, cross-functional communication, and stakeholder alignment.
- Strategic thinking; manage multiple priorities while ensuring detail/compliance.
- Understanding of facility/utility systems’ impact on GMP operations.
- Working knowledge of commissioning/validation and IQ/OQ/PQ development/execution.
- Proficiency with project management tools and MS Office; CAD/BIM familiarity a plus.
Working Environment:
- On-site as noted in the offer letter; Monday–Friday during standard business hours (flexibility with manager approval).
- Mobility required for office and construction/plant environments; lift/carry up to 20 lbs.
Benefits/Compensation (explicitly stated):
- Discretionary bonus and equity award.
- Annual base pay range: $148,500–$165,000.
Application Instructions:
- Application window anticipated to close 60 days from posting (or sooner if filled/closed).