Principal Engineer, AI/Software Support, Pooled Screening Core, Cell & Genetic Medicines
Johnson & Johnson Innovative Medicine
September 29, 2026
Full-time
Remote
Worldwide
IT
Role: Principal Engineer specializing in AI/software support within Johnson & Johnson's Cell & Genetic Medicines high-throughput screening team, focusing on pooled and arrayed workflows for cell therapy discovery. Responsibilities: design and scale software, data, and AI solutions connecting automation, analytical instruments, and enterprise systems; develop applications, APIs, data pipelines, and AI-enabled tools; implement best practices in software architecture, security, and lifecycle management; collaborate cross-functionally with scientists, automation engineers, and IT; mentor teams on software engineering and AI usage; and prioritize opportunities to enhance scientific productivity and operational efficiency. Requirements: Bachelor's degree in computer science, data science, bioinformatics, or related field with extensive experience in complex scientific software systems; proven experience integrating AI/ML and generative AI into production software; proficiency with AWS and data management; strong systems thinking and stakeholder management skills; able to work in multidisciplinary teams and travel 10–15%. Preferred: experience in drug discovery, cell therapy, high-throughput screening, laboratory automation, and scientific data standards; hands-on with ELN systems like Benchling. High-Value: focus on biotherapeutics, cell and genetic medicines, high-throughput screening, and AI-driven discovery tools. Work setup: Remote (US), with travel to Spring House, PA; La Jolla, CA; and Cambridge, MA.