Principal Engineer, AI/Software Support, Pooled Screening Core, Cell & Genetic Medicines

Role: Principal Engineer leading AI/software development within Johnson & Johnson's Cell & Genetic Medicines high-throughput screening team, supporting pooled and arrayed workflows for cell therapy discovery. Responsibilities: design and implement scalable software architecture connecting lab automation, analytical instruments, and enterprise systems; develop applications, data pipelines, APIs, and visualization tools; integrate AI/ML and generative AI models to enhance scientific insights and operational efficiency; establish engineering best practices; collaborate across Discovery Research, IT, and other units; mentor team members and influence technical strategy. Requirements: Bachelor's in computer science, data science, bioinformatics, or related field; extensive experience in complex software systems in biotech/pharma, with proven AI/ML integration skills; proficiency with AWS cloud services; strong systems thinking and stakeholder communication. Preferred: experience supporting drug discovery, cell therapy, laboratory automation, high-dimensional biological datasets, and ELN integration (e.g., Benchling). High-value specifics include focus on cell & gene therapies, high-throughput screening, and AI-enabled workflows in a regulated environment. Work setup: Remote within the US with 10–15% travel to locations such as Spring House, PA; La Jolla, CA; and Cambridge, MA. Success is measured by enabling a connected, efficient, data-driven screening environment that accelerates candidate selection and scales innovative screening technologies.