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Principal Engineer 1, Data Platforms (Microsoft Fabric)

Halozyme, Inc.
October 2, 2026
Full-time
Remote friendly (San Diego, CA)
Worldwide
$185,000 - $185,000 USD yearly
IT
Role: Principal Engineer 1, Data Platforms at Halozyme, leading the design, development, and operational management of the company's Microsoft Fabric-based data lakehouse. Responsibilities include architecting workspace topology, building production-grade data pipelines from diverse source systems (e.g., Veeva, LIMS, CTMS), providing technical mentorship, and partner engagement across R&D, Manufacturing, and Commercial functions. The role emphasizes ensuring platform reliability, data quality, and delivering actionable insights via semantic layers like Power BI. Key tasks involve establishing support models, defining KPIs, enforcing engineering standards, and managing vendor reviews. Required qualifications include a Bachelor's in Computer Science or related field with 10+ years in data engineering, 2+ years leading data teams, strong expertise in Microsoft Fabric, PySpark, T-SQL, Python, and experience with medallion architectures at enterprise scale. Preference for candidates with biopharma, life sciences, or GxP experience, familiarity with pharma source systems (Veeva, LIMS, CTMS), and exposure to AI/ML workloads. The role reports to senior leadership, with a focus on building scalable, reliable data infrastructure supporting biopharmaceutical R&D and manufacturing activities. Work setup is unspecified, but the role involves technical leadership and collaboration across multiple teams.