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Principal Electrical Engineering Architect

Seer
August 08, 2026
On-site
Redwood City, CA
IT
Responsibilities & Goals:
- Architect the comprehensive electrical system layout for a novel TOF mass spectrometer.
- Specify high-voltage DC power supply architecture (up to 15 kV) for precision ion optics and flight tubes.
- Develop robust high-voltage RF systems (~1–2 MHz, ~4 kV amplitudes) for ion guides, funnels, quadrupoles, and traps; ensure high stability and low temperature drift.
- Implement grounding, shielding, and isolation strategies to mitigate RF pickup on lenses and signal lines.
- Engineer component-level solutions to minimize electronic noise, voltage ripple, and thermal drift affecting ion beam trajectories, mass resolution, and mass accuracy.
- Oversee integration of high-voltage electronics within high-vacuum systems; define system-level cabling and interconnect strategies.

Background/Qualifications:
- Deep hands-on experience with mass spectrometry (sample prep through data analysis) and entrepreneurial orientation with strong teamwork and integrity.

Requirements:
- Master’s degree or Ph.D. in Electrical Engineering, Applied Physics, or closely related field.
- 10+ years in an academic or life-sciences laboratory setting (biotech start-up experience preferred).
- Demonstrated architectural design experience with mass spectrometers and similar technologies.
- Proven track record implementing high-voltage DC and high-amplitude RF electronics.
- Practical knowledge of signal integrity, ultra-low noise analog circuit design, and precision timing circuits.
- Deep understanding of guiding low-energy ion beams without phase-space distortion.
- Strong written and oral communication; cross-functional, timely communication.
- Self-starter who works well independently and collaboratively; meets deadlines in a fast-paced environment.

Physical requirements:
- Prolonged sitting/standing; lift/carry up to 15 pounds; wear PPE.

Compensation:
- Base pay range: $175,000–$205,000; eligible for bonus, benefits, and stock option plan.