Portfolio Lead – Fabry and Gaucher

Role Summary

The Portfolio Lead for Fabry and Gaucher will serve as a strategic leader and visionary for Gaucher and Fabry products, driving enterprise-wide brand strategy with a customer-centric approach. This senior executive will define and execute product positioning and comprehensive strategic roadmaps based on deep market intelligence, patient journey insights, and the value delivered by products and services to improve patient outcomes. This leader will provide strategic direction across GTM models and will lead an Associate Director of Marketing, fostering talent development and organizational capability building. Location: Cambridge, MA.

Responsibilities

• Strategic Leadership & Vision: Architect and drive the long-term strategic vision for Gaucher & Fabry brands, establishing enterprise-wide priorities that align with organizational objectives and market opportunities. Provide thought leadership that shapes the future direction of the rare disease portfolio.
• Brand Portfolio Management: Lead comprehensive brand planning, budgeting, KPI development and tracking, forecasting, and financial stewardship across multiple brands. Drive strategic resource allocation decisions and investment prioritization to maximize portfolio value and market impact.
• Cross-Functional Leadership & Influence: Serve as the primary strategic partner and liaison with global GBL, country teams, PSS, patient marketing, Account Engagement marketing, and health system marketing teams. Lead and influence senior-level stakeholders across the organization, driving alignment on critical brand decisions and strategic initiatives.
• Market Intelligence & Strategic Insights: Develop and synthesize sophisticated insights on disease areas, market dynamics, and competitive landscapes using comprehensive US and global data sources. Transform complex data into actionable strategic recommendations that drive competitive advantage.
• Customer & Market Strategy: Orchestrate insights gathering across marketing channels, customer segments, and digital platforms. Lead the development of deep customer understanding to articulate compelling value propositions that address unmet needs in the rare disease category.
• Competitive Strategy & Market Positioning: Continuously monitor and analyze the competitive environment, pipeline activities, and market trends. Develop proactive strategies to address competitive threats and capitalize on market opportunities, ensuring organizational readiness for market shifts.
• Patient Journey & Market Development: Create comprehensive, end-to-end patient journey strategies, including innovative approaches to patient identification, diagnosis acceleration, and treatment optimization. Drive market development initiatives that expand access and improve patient outcomes.
• Commercial Strategy Execution: Develop and execute sophisticated commercial brand strategies informed by market intelligence, customer insights, and competitive analysis. Build adaptive strategies that can be rapidly deployed in response to competitive entrants and market dynamics.
• Governance & Organizational Alignment: Lead cross-functional governance forums and strategic planning sessions to ensure enterprise-wide alignment. Drive organizational consensus on strategic priorities and provide strategic input to support accurate product demand forecasts and business planning.
• Financial Stewardship: Manage substantial brand marketing budgets with strategic oversight. Provide senior-level input on annual planning processes, ensuring alignment with global marketing strategies, regulatory requirements, and business objectives. Drive ROI optimization across all brand investments.
• Launch Excellence: Lead launch readiness initiatives with strategic oversight, including competitive assessment, target product profile (TPP) development, market access strategy, and comprehensive pre-launch planning. Ensure organizational preparedness for successful product introductions.
• Team Leadership & Development: Provide strategic leadership and mentorship to an Associate Director of Marketing, fostering professional growth, strategic thinking capabilities, and leadership development. Build organizational capability and talent density within the marketing function.

Qualifications

• Education: Bachelor's degree in marketing, business, technology, or life sciences required; MBA or advanced degree strongly preferred
• Experience: 12+ years of progressive marketing, sales, or insights & analytics experience in the pharmaceutical or biotechnology industry, with demonstrated success in senior leadership roles driving strategic initiatives
• Leadership Excellence: Proven track record of leading and developing high-performing teams, with experience managing marketing professionals and driving organizational capability building
• Strategic Acumen: Exceptional strategic decision-making capabilities with a history of innovation, complex problem-solving, and successfully navigating ambiguous situations without clear precedent. Demonstrated ability to think strategically while executing tactically
• Cross-Functional Leadership: Extensive experience working within large-scale, complex multidisciplinary organizations with proven ability to influence and drive alignment across senior stakeholders without direct authority
• Launch Strategy Expertise: Deep expertise in product and launch strategy development and execution, with demonstrated success in building and growing brands in competitive markets
• Rare Disease or Specialty Experience: Experience in rare disease, specialty therapeutics, or complex treatment paradigms strongly preferred
• Global Perspective: US, Global, and Ex-US experience preferred, with understanding of diverse market dynamics and regulatory environments
• Executive Presence: Strong executive presence with ability effectively with C-suite leaders, external stakeholders, and key opinion leaders

Additional Requirements

• Travel: Up to 25% travel within US and internationally as needed