PK/PD Principal Scientist

Role Summary

The Zoetis Veterinary Medicine Research & Development (VMRD) is seeking a talented PK/PD modeler to join our team to discover and develop novel protein therapeutics for veterinary medicine. The successful candidate will be primarily responsible for providing PK/PD modeling and simulation support for projects from early research through late-stage development. This position will require a highly motivated and independent leader who can effectively collaborate with other team members to advance projects.

Responsibilities

• Independently develop PK, population PK, PK/PD, PBPK, and/or QSP models using in vivo study data from different veterinary species, employing NONMEM, R, Monolix or related software.
• Collaborate with project teams to use modeling and simulation to help design, optimize or prosecute in vivo PK, PK/PD and clinical studies in line with the strategic direction of the project.
• Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
• Provide concise technical reports summarizing modeling and simulation work.
• Present research results to scientific teams, management, and regulatory agencies.
• Write sections of regulatory submissions and respond to inquiries from regulatory agencies.

Qualifications

• Ph.D in bioengineering, mathematics, pharmacology or related field with 4 or more years of relevant pharmaceutical development experience
• Proven ability to apply PBPK, QSP or population PK modeling using NONMEM, R, or related software.
• Must have excellent verbal & written communication skills
• Self-starter, able to prioritize work and work efficiently with minimal supervision.

Desirable Skills

• Strong background in statistics.
• Experience analyzing PK/PD of biotherapeutics (protein therapeutics).
• Self-starter, able to prioritize work and work efficiently with minimal supervision.
• Experience interacting with regulatory agencies.
• Working knowledge of bioanalytical assays is helpful.