Operations Manager
Legend Biotech
June 24, 2026
On-site
Raritan, NJ
Operations
Role Overview
The CAR-T Operations 2nd Shift Manager is an exempt position within Technical Operations. Responsible for overseeing production of a personalized cell therapy to support clinical and commercial requirements in a sterile cGMP environment. Onsite; Monday–Friday on the 2nd shift.
Key Responsibilities
- Oversee cell therapy production; ensure safe, compliant manufacturing per cGMP.
- Site management resource/point of contact for all 2nd shift employees.
- Primary point of contact for 2nd shift Technical Operations supervisors.
- Take direction from Associate Director and/or Senior Managers of process areas.
- Oversee hiring, development, performance management; assign staff to execute daily schedules.
- Create/revise operational procedures (manufacturing work instructions, master batch records, forms).
- Manage multiple work centers; ensure high-quality, compliant product supply and monitor production metrics.
- Support manufacturing investigations; manage change controls; maintain inspection readiness; support regulatory inspections.
- Partner with Manufacturing, Engineering, and Quality to execute daily schedules.
- Lead facility operating review meetings; drive continuous improvement and efficiencies; own department projects.
- Establish relationships with internal/external stakeholders across all levels.
Requirements
- Bachelor’s degree in Engineering or related field (or equivalent experience).
- 5+ years operations experience in a cGMP biotech/biopharma environment, including 3+ years supervisory experience; Cell/Gene Therapy preferred.
- Ability to build partnerships in a matrix environment with external collaborators.
- Ability to independently prioritize/manage multiple tasks and cross-functional issues.
- Manage shifting priorities/deadlines in a fast-paced environment; provide clear direction.
- Clear verbal/written communication.
- Strong analytical/problem-solving/critical thinking; lead as change agent.
- Basic project management; responsiveness; passion for creating new medicines.
- Operational Excellence and/or Lean Manufacturing is an asset.
- Ability to accommodate shift work, daily overtime/weekends, and unplanned overtime.
- Deep GMP compliance & regulatory knowledge (FDA/EMA and global).
- Familiarity with manufacturing systems (MES, ERP) and digital transformation.
Benefits
- Medical, dental, and vision insurance; 401(k) with match (vests day one); 8 weeks paid parental leave after 3 months; paid time off (vacation, personal, sick, floating holidays, 11 company holidays); additional voluntary benefits including flexible spending/HSAs, life/AD&D, short- and long-term disability, legal assistance, and supplemental plans.
Pay Range (Base Pay)
- $127,313–$167,099 USD
The CAR-T Operations 2nd Shift Manager is an exempt position within Technical Operations. Responsible for overseeing production of a personalized cell therapy to support clinical and commercial requirements in a sterile cGMP environment. Onsite; Monday–Friday on the 2nd shift.
Key Responsibilities
- Oversee cell therapy production; ensure safe, compliant manufacturing per cGMP.
- Site management resource/point of contact for all 2nd shift employees.
- Primary point of contact for 2nd shift Technical Operations supervisors.
- Take direction from Associate Director and/or Senior Managers of process areas.
- Oversee hiring, development, performance management; assign staff to execute daily schedules.
- Create/revise operational procedures (manufacturing work instructions, master batch records, forms).
- Manage multiple work centers; ensure high-quality, compliant product supply and monitor production metrics.
- Support manufacturing investigations; manage change controls; maintain inspection readiness; support regulatory inspections.
- Partner with Manufacturing, Engineering, and Quality to execute daily schedules.
- Lead facility operating review meetings; drive continuous improvement and efficiencies; own department projects.
- Establish relationships with internal/external stakeholders across all levels.
Requirements
- Bachelor’s degree in Engineering or related field (or equivalent experience).
- 5+ years operations experience in a cGMP biotech/biopharma environment, including 3+ years supervisory experience; Cell/Gene Therapy preferred.
- Ability to build partnerships in a matrix environment with external collaborators.
- Ability to independently prioritize/manage multiple tasks and cross-functional issues.
- Manage shifting priorities/deadlines in a fast-paced environment; provide clear direction.
- Clear verbal/written communication.
- Strong analytical/problem-solving/critical thinking; lead as change agent.
- Basic project management; responsiveness; passion for creating new medicines.
- Operational Excellence and/or Lean Manufacturing is an asset.
- Ability to accommodate shift work, daily overtime/weekends, and unplanned overtime.
- Deep GMP compliance & regulatory knowledge (FDA/EMA and global).
- Familiarity with manufacturing systems (MES, ERP) and digital transformation.
Benefits
- Medical, dental, and vision insurance; 401(k) with match (vests day one); 8 weeks paid parental leave after 3 months; paid time off (vacation, personal, sick, floating holidays, 11 company holidays); additional voluntary benefits including flexible spending/HSAs, life/AD&D, short- and long-term disability, legal assistance, and supplemental plans.
Pay Range (Base Pay)
- $127,313–$167,099 USD