Obesity Research Scientist - Boston

Role Summary

We are seeking a skilled and motivated individual to help build a highly collaborative drug discovery and development team in the Obesity research group in Boston. The successful candidate will use a strong in vivo pharmacology background and complementary laboratory and/or in vitro skills to support discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. You will be responsible for setting up critical capabilities in the laboratory setting and collaborating with scientists across departments to achieve project and department goals. Location: Boston.

Responsibilities

• Plan and independently implement in vivo experiments to support preclinical characterization and evaluation of targets/pathways that regulate energy balance.
• Perform routine rodent handling, dosing, and small animal surgeries, including but not limited to parenteral routes of administration.
• Perform molecular and biochemical assessments on ex vivo samples in collaboration with colleagues in other departments.
• Function independently, work within a team-oriented lab environment, and participate in cross-functional project teams.
• Maintain accurate record-keeping, perform independent data analysis, and report data in written and oral formats.
• Ensure full compliance with Lilly Research Policies and complete all required training activities within the specified timeframe.

Qualifications

• Required: B.S. and/or M.S. in biology or a closely related field with 4+ years of experience
• Preferred: A background in the biology and physiology of energy balance regulation and metabolic disease – relevant models of obesity
• Preferred: Experience with in situ hybridization, various assay detection technologies (fluorescence, luminescence, FRET, alpha-screen, ELISA assays), and the ability to implement and validate new assay technologies
• Preferred: Experience with imaging techniques and/or flow cytometry
• Preferred: Experience with assays to assess mitochondrial function including high-capacity respirometry
• Preferred: Experience in primary cell isolation and downstream cell line work, including functional, molecular, and screening assays
• Preferred: Demonstrated ability to work on cross-functional teams and projects
• Preferred: Strong communication skills and experience presenting data in a team environment

Skills

• In vivo pharmacology
• Laboratory and/or in vitro skills
• Molecular and biochemical assay capabilities
• Imaging techniques and flow cytometry
• Primary cell isolation and downstream cell line work
• Cross-functional collaboration and strong communication