Medical Director, Kidney Disease, Early Clinical Development CVRM

Role: Medical Director specializing in Kidney Disease within AstraZeneca's CVRM Translational Medicine & Clinical Development. Primary objectives include leading early phase (I-II) global clinical trials targeting kidney disease, integrating preclinical insights, and ensuring scientific, safety, and regulatory compliance. Responsibilities encompass clinical trial strategy, protocol design, study conduct, data interpretation, and advancing surrogate endpoints and biomarkers. The role involves cross-functional collaboration across CVRM programs in heart failure, T2D, obesity, and metabolic disorders, emphasizing translational research and early human target validation. Qualifications: MD, MBBS, or MD/PhD with at least 2 years of clinical research experience in academia or biotech/pharma, with expertise in kidney diseases and early clinical trial oversight. Strong knowledge of biomarkers, surrogate endpoints, and biostatistics is required, supported by a publication record. Preferred skills include leadership in cross-disciplinary teams, stakeholder engagement, and experience in translational/early-phase clinical development. High-value specifics: focus on kidney disease, early phase (I-II), global trials, biomarker development, and cross-therapeutic collaboration across cardiovascular and metabolic areas. Work setup involves a hybrid model (3 days onsite in Gaithersburg, MD), with no specific travel requirements mentioned.