Integrated Evidence Generation (IEP/RWE/Epi) Lead

Role Summary

The leader in this role will provide strategic leadership and drive innovation in medical study orchestration and design, including integrated evidence planning, research design, and implementation to ensure end-to-end evidence generation activities are strategically aligned, methodologically rigorous, and operationally efficient by harmonizing study design and delivery approaches, thereby strengthening the organization’s ability to support regulatory, clinical, payer, and patient-centered decision-making globally.

Responsibilities

• Oversee cross-functional teams specializing in Integrated Evidence Planning (IEP), RWE/epidemiology study design, patient-centered research design and execution, and RWE/epidemiology methods development and innovation
• Set strategic direction for study design and orchestration, ensuring alignment with portfolio and therapeutic area objectives
• Drive innovation in methodologies including pragmatic trials, hybrid designs, synthetic controls, RWE/epidemiology methods, and patient-centered approaches
• Foster cross-functional collaboration among epidemiology, therapeutic area, and RWE innovation teams, as well as other internal and external stakeholders
• Partner across Medical, Clinical, Regulatory, Market Access/HEOR, Digital, and Commercial functions to deliver integrated evidence strategies
• Communicate effectively with senior leadership and key stakeholders to facilitate decision-making and alignment
• Ensure cost-effective evidence optimization across multiple internal and external stakeholders to demonstrate comparative effectiveness, safety, and value of Pfizer's medicines and vaccines
• Apply data, technology and advanced analytics such as AI to improve quality and economics of study design and orchestration
• Drive performance on metrics including R&D efficiency, effectiveness and equity
• Serve as an enterprise thought leader to internal stakeholders and external partners, shaping industry standards for evidence generation
• Lead resource stewardship, risk management, and capability building to ensure sustainable and scalable impact
• Define and track key metrics to measure success and drive continuous improvement
• Member of Medical Evidence Development Leadership team
• Partners with leadership across Medical, Clinical, Regulatory, Market Access/HEOR, Digital and Commercial

Qualifications

• Advanced degree, such as PhD in Epidemiology or MD
• 15+ years of experience in clinical research or evidence generation within pharma or biotech, including 5+ years leading study design or protocol development
• Expertise in both traditional clinical trials and RWE methodologies
• Experience with decentralized, hybrid, and pragmatic trials strongly preferred
• Deep understanding of global regulatory and ethical requirements for clinical and non-interventional studies
• Proven track record of cross-functional leadership and in a highly matrixed environment and communicating effectively with senior leadership and key stakeholders to facilitate decision-making and alignment