Health Economics & Outcomes Research Associate Director, Pain
Vertex Pharmaceuticals
August 10, 2026
Remote friendly (Boston, MA)
United States
Market Access
General Summary:
The Health Economics & Outcomes Research Associate Director will lead the development and execution of Health economics and outcomes research studies in support of Vertex’s products. Reports to the Director, HEOR Pain.
Key Duties and Responsibilities:
- Lead execution of complex HEOR evidence generation, including cost-effective analysis and budget impact models, prospective/retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation, and other research to support asset value.
- Gather and synthesize insights from payers, KOLs, and HEOR experts; stay current with scientific and policy trends and best practices; apply expertise to strategy planning.
- Apply best practices to inform the design of Vertex observational research studies.
- Collaborate with medical communications on publication strategy to ensure timely, maximum-impact dissemination of HEOR evidence.
- Partner with Global Pricing and Market Access to support production of GVD and Value Narrative.
Knowledge and Skills:
- Strong track record of publication in peer-reviewed journals.
- Technical expertise in HEOR; ability to formulate and lead rigorous, creative research projects using best HEOR practices.
- Strong verbal and written communication skills; ability to present and persuade across diverse audiences.
- Ability to apply knowledge of the US healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and build evidence-generation strategies.
- Understanding of the pharmaceutical industry’s legal/regulatory environment with a compliance/ethical conduct history.
Education and Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent combination of education and experience).
The Health Economics & Outcomes Research Associate Director will lead the development and execution of Health economics and outcomes research studies in support of Vertex’s products. Reports to the Director, HEOR Pain.
Key Duties and Responsibilities:
- Lead execution of complex HEOR evidence generation, including cost-effective analysis and budget impact models, prospective/retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation, and other research to support asset value.
- Gather and synthesize insights from payers, KOLs, and HEOR experts; stay current with scientific and policy trends and best practices; apply expertise to strategy planning.
- Apply best practices to inform the design of Vertex observational research studies.
- Collaborate with medical communications on publication strategy to ensure timely, maximum-impact dissemination of HEOR evidence.
- Partner with Global Pricing and Market Access to support production of GVD and Value Narrative.
Knowledge and Skills:
- Strong track record of publication in peer-reviewed journals.
- Technical expertise in HEOR; ability to formulate and lead rigorous, creative research projects using best HEOR practices.
- Strong verbal and written communication skills; ability to present and persuade across diverse audiences.
- Ability to apply knowledge of the US healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and build evidence-generation strategies.
- Understanding of the pharmaceutical industry’s legal/regulatory environment with a compliance/ethical conduct history.
Education and Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent combination of education and experience).