Health Economics & Outcomes Research Associate Director (HYBRID)

Role Summary

Health Economics & Outcomes Research Associate Director (HYBRID) at Vertex. Participate in shaping and executing HEOR strategies to optimize the value proposition for Vertex’s Cystic Fibrosis and early pipeline assets through development, launch, and post-launch phases. Reports to the Senior Director HEOR, CF and Early Pipeline.

Responsibilities

• Leads execution of complex HEOR evidence generation studies, including prospective and retrospective observational studies, systematic literature reviews, cost-effective analyses and budget impact models, indirect treatment comparisons, COA strategy, PRO measure development and validation, as needed, to support asset value.
• Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; accountable for study design, data analysis and the quality of the evidence produced; project management to ensure studies are delivered on time and within budget.
• Collaborates with medical communications teams on publication strategy and ensures dissemination of HEOR evidence is timely and impactful.
• Partners with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier).

Qualifications

• Required: Advanced degree (PhD, MD, Master's, MPH, or PharmD) in a relevant discipline; typically 8 years of experience with substantial HEOR background.
• Preferred: Strong track record of publication in peer-reviewed journals; experience in COA measurement strategy, PRO development/validation and qualitative research methodology; ability to apply knowledge of US healthcare system and global health technology appraisal requirements; understanding of regulatory environment and compliance.

Skills

• Technical expertise in HEOR; ability to formulate and lead creative research projects with rigorous scientific conduct.
• Strong verbal and written communication skills; ability to present difficult concepts and adapt style to diverse audiences.
• Experience collaborating across functions to identify evidence gaps and develop evidence generation strategies.

Education

• Advanced degree (PhD, MD, Master's, MPH, or PharmD) in a relevant discipline.

Additional Requirements

• No specific travel or physical demands are listed as essential beyond standard expectations for hybrid roles.