Health Economics & Outcomes Research Associate Director, Cell & Gene Therapy
Vertex Pharmaceuticals
August 09, 2026
Remote friendly (Boston, MA)
United States
Market Access
General Summary:
Vertex seeks a Health Economics & Outcomes Research Associate Director, Cell and Gene Therapy (CGT) to lead development and execution of HEOR studies supporting CGT products in hemoglobinopathies and type 1 diabetes. Reports to the Senior Director Global HEOR, CGT.
Key Duties And Responsibilities:
- Lead others executing complex HEOR evidence generation: cost-effective analyses and budget impact models; prospective and retrospective observational studies; ITCs; meta-analyses and systematic reviews; patient-reported outcome measure development/validation; and other research to support asset value.
- Gather and synthesize payer, KOL, and HEOR expert insights; stay current on scientific/policy trends and apply to strategy planning.
- Provide key input using best practices to design Vertex observational research studies.
- Collaborate with medical communications on publication strategy; ensure timely, high-impact dissemination of HEOR evidence.
- Partner with Global Value and Access Strategy to support production of GVD and Value Narrative.
Knowledge And Skills:
- Strong publication track record in peer-reviewed journals.
- Technical HEOR expertise; ability to formulate/lead rigorous, best-practice HEOR research.
- Strong written and verbal communication skills, including presenting and persuading across audiences.
- Ability to apply US healthcare system and global health technology appraisal requirements, and clinical development knowledge to identify evidence gaps and develop evidence generation strategies.
- Understanding of pharmaceutical industry legal/regulatory environment and compliance.
Education And Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent).
- Prior cell/gene therapy and/or hemoglobinopathies and type 1 diabetes experience preferred.
Pay Range:
- $176,000 - $264,000
Vertex seeks a Health Economics & Outcomes Research Associate Director, Cell and Gene Therapy (CGT) to lead development and execution of HEOR studies supporting CGT products in hemoglobinopathies and type 1 diabetes. Reports to the Senior Director Global HEOR, CGT.
Key Duties And Responsibilities:
- Lead others executing complex HEOR evidence generation: cost-effective analyses and budget impact models; prospective and retrospective observational studies; ITCs; meta-analyses and systematic reviews; patient-reported outcome measure development/validation; and other research to support asset value.
- Gather and synthesize payer, KOL, and HEOR expert insights; stay current on scientific/policy trends and apply to strategy planning.
- Provide key input using best practices to design Vertex observational research studies.
- Collaborate with medical communications on publication strategy; ensure timely, high-impact dissemination of HEOR evidence.
- Partner with Global Value and Access Strategy to support production of GVD and Value Narrative.
Knowledge And Skills:
- Strong publication track record in peer-reviewed journals.
- Technical HEOR expertise; ability to formulate/lead rigorous, best-practice HEOR research.
- Strong written and verbal communication skills, including presenting and persuading across audiences.
- Ability to apply US healthcare system and global health technology appraisal requirements, and clinical development knowledge to identify evidence gaps and develop evidence generation strategies.
- Understanding of pharmaceutical industry legal/regulatory environment and compliance.
Education And Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent).
- Prior cell/gene therapy and/or hemoglobinopathies and type 1 diabetes experience preferred.
Pay Range:
- $176,000 - $264,000