Engineer III
Takeda
Remote friendly (Lexington, MA)
United States
$86,500 - $135,960 USD yearly
Operations
Role Summary
Engineer III based in Lexington, MA. Full-time role with up to 20% remote work.
Responsibilities
- Independently carry out bioreactor operations across scales from 250 ml to 10 L.
- Prepare experimental protocols and support tech transfer of developed cell culture processes to pilot and manufacturing facilities.
- Design experiments, interpret data, identify complex technical issues, and implement solutions under supervision.
- Contribute to technical reports by writing and consolidating technical documents; participate in cross-functional projects.
- Support process development, optimization, characterization, troubleshooting, large-scale studies, and project goals.
- Support technology transfer through documentation, batch record reviews, and cross-functional coordination.
- Contribute to evaluation of new technology/equipment applicable across programs.
- Document data per company guidelines; draft technical reports, memos, procedures, protocols, and presentations; present to department and project teams.
- Execute bioreactor operations, clarifications, and purification using high-throughput systems (e.g., AMBR250, Tecan).
Qualifications
- Required: Master’s degree in Chemistry, Biology, Pharmacy, Engineering, or related Pharmaceutical Science.
- Required: Experience executing bioreactor operations, primary clarification, and purification using high-throughput systems (e.g., AMBR250, Tecan); design experiments to assess and optimize process performance; interpret data and implement solutions.
- Required: Collaboration with cross-functional teams to support tech transfer to Pilot, Manufacturing, and external CDMOs; author and revise technical documents including SOPs and development reports.
- Required: Cross-training team members on analytical instruments and techniques; conduct product quality testing using tools such as Solo-VPE, Lunatic, HPLC, UPLC, and UV spectrophotometer.
Education
- Master’s degree in Chemistry, Biology, Pharmacy, Engineering, or related Pharmaceutical Science.
Skills
- Bioreactor operations across multiple scales
- Tech transfer and cross-functional collaboration
- Experimental design and data interpretation
- Documentation and technical writing
- Quality testing and analytical instrumentation (HPLC, UPLC, UV, Solo-VPE, Lunatic)
Additional Requirements
- Location: Lexington, MA
- Travel: Not specified
- Work arrangement: Full-time; up to 20% remote work