Director, FP&A - Commercial
Amylyx Pharmaceuticals
August 21, 2026
Remote friendly (Cambridge, MA)
United States
Corporate Functions
Responsibilities:
- Serve as the primary finance business partner to Commercial leadership, providing financial guidance and decision support to drive growth and profitability.
- Lead the annual operating plan, quarterly forecasts, and long-range planning processes for Commercial functions.
- Develop and maintain financial models, forecasts, and business analytics to evaluate revenue performance, commercial investments, pricing strategies, and growth opportunities.
- Analyze commercial performance metrics and business drivers (revenue growth, sales productivity, pipeline conversion, payer mix, pricing, customer economics, and operating expenses).
- Provide executive-level financial reporting and performance insights with recommendations to improve business outcomes.
- Partner with Commercial leaders to establish performance targets and accountability measures; monitor progress vs. budget, forecast, and strategy.
- Lead strategic investment analyses and business case development to support resource allocation and market expansion.
- Drive continuous improvement of FP&A processes, forecasting methodologies, reporting capabilities, and financial systems.
Required Qualifications:
- Bachelor’s degree in finance or accounting.
- 10+ years of progressive FP&A/finance business partnering/commercial finance experience, including leadership responsibility.
- Life sciences/biotech/pharma/healthcare experience supporting commercial operations, revenue forecasting, pricing strategy, and commercialization.
- Deep expertise in budgeting, forecasting, long-range planning, financial modeling, and performance management.
- Proven ability to influence senior leaders as a trusted advisor.
- Ability to build sophisticated models and synthesize complex data into actionable insights.
- Strong understanding of revenue growth drivers, pricing, sales effectiveness, customer economics, payer dynamics, and market access.
- Ability to translate complex financial information into clear executive narratives and recommendations.
- Ability to anticipate risks, identify opportunities, challenge assumptions, and deliver data-driven solutions.
Preferred Requirements:
- MBA and/or CPA.
Work Location/Conditions:
- Remote work within the United States (certain states excluded).
- Travel to Cambridge, MA several times per year and attend other events as needed.
- Reliable remote work setup (privacy, reliable internet, phone, ability to video conference).
Compensation:
- Estimated pay range: $201,000–$226,000 USD.
- Serve as the primary finance business partner to Commercial leadership, providing financial guidance and decision support to drive growth and profitability.
- Lead the annual operating plan, quarterly forecasts, and long-range planning processes for Commercial functions.
- Develop and maintain financial models, forecasts, and business analytics to evaluate revenue performance, commercial investments, pricing strategies, and growth opportunities.
- Analyze commercial performance metrics and business drivers (revenue growth, sales productivity, pipeline conversion, payer mix, pricing, customer economics, and operating expenses).
- Provide executive-level financial reporting and performance insights with recommendations to improve business outcomes.
- Partner with Commercial leaders to establish performance targets and accountability measures; monitor progress vs. budget, forecast, and strategy.
- Lead strategic investment analyses and business case development to support resource allocation and market expansion.
- Drive continuous improvement of FP&A processes, forecasting methodologies, reporting capabilities, and financial systems.
Required Qualifications:
- Bachelor’s degree in finance or accounting.
- 10+ years of progressive FP&A/finance business partnering/commercial finance experience, including leadership responsibility.
- Life sciences/biotech/pharma/healthcare experience supporting commercial operations, revenue forecasting, pricing strategy, and commercialization.
- Deep expertise in budgeting, forecasting, long-range planning, financial modeling, and performance management.
- Proven ability to influence senior leaders as a trusted advisor.
- Ability to build sophisticated models and synthesize complex data into actionable insights.
- Strong understanding of revenue growth drivers, pricing, sales effectiveness, customer economics, payer dynamics, and market access.
- Ability to translate complex financial information into clear executive narratives and recommendations.
- Ability to anticipate risks, identify opportunities, challenge assumptions, and deliver data-driven solutions.
Preferred Requirements:
- MBA and/or CPA.
Work Location/Conditions:
- Remote work within the United States (certain states excluded).
- Travel to Cambridge, MA several times per year and attend other events as needed.
- Reliable remote work setup (privacy, reliable internet, phone, ability to video conference).
Compensation:
- Estimated pay range: $201,000–$226,000 USD.