Director Engineering
Amgen
August 29, 2026
Remote friendly (Holly Springs, NC)
United States
IT
What You Will Do
As Director, Engineering at Amgen North Carolina (ANC), you will lead the site’s Engineering, Automation, Maintenance, and Instrumentation capabilities to deliver safe, compliant, reliable, and efficient drug-substance manufacturing operations.
Responsibilities:
- Provide strategic and operational leadership for Engineering, Automation, Maintenance, and Instrumentation.
- Ensure safe, reliable, and compliant performance of manufacturing equipment, automation systems, and instrumentation.
- Establish and execute site asset-management strategy (preventive/predictive maintenance, calibration, reliability, spare parts, lifecycle management).
- Lead engineering compliance program (inspection readiness; adherence to cGMP, EHS, quality-system, and regulatory requirements).
- Partner with Site Operations, Quality, Digital/Automation, Supply Chain, and Capital Project Delivery to integrate assets and implement site strategy.
- Lead technical support (system ownership, troubleshooting, root-cause analysis, reliability improvement, corrective actions).
- Establish governance for maintenance execution/work management (planning/scheduling, backlog, work-order quality, contractor oversight, performance metrics).
- Develop/manage/forecast operating and capital budgets; prioritize against safety, quality, supply, reliability, and lifecycle risks.
- Build and lead a high-performing organization; set accountabilities, develop talent, and create succession plans.
- Manage service-provider relationships to ensure safe, compliant, quality work.
- Escalate significant risks with options/recommendations.
- Drive continuous improvement (lean maintenance, digital tools, reliability engineering, sustainability initiatives).
- Represent ANC in global networks; adopt leading practices.
- Make timely, risk-based decisions to protect patients, employees, compliance, and supply.
What We Expect Of You
Basic Qualifications:
- Doctorate + 4 years Engineering experience OR Master’s + 8 years OR Bachelor’s + 10 years.
- At least 4 years directly managing people and/or leadership experience leading teams/projects/programs or allocating resources (may run concurrently).
Preferred Qualifications:
- 12+ years in engineering/maintenance/automation/instrumentation/utilities/reliability/asset-management in pharma/biotech or similarly regulated manufacturing.
- 7+ years leadership (direct management; accountability for multi-function teams, contractors, service providers).
- Site-level E/A/M/I leadership supporting GMP manufacturing.
- Proven reliability/compliance accountability for equipment, automation platforms, instrumentation, clean utilities, and support systems.
- CMMS experience (e.g., Maximo) for maintenance/calibration/reliability/lifecycle/spare parts.
- Experience building technical orgs (workforce strategy, capability development, succession planning, contractor models, vendor governance).
- Track record leading through inspections, quality events, deviations, root-cause investigations, and CAPA.
- Capital project partnership (design/commissioning/qualification/turnover/operational readiness).
- Ownership of operating/capital budgets and cost forecasts/business cases.
- Implementing engineering excellence/reliability/digital/sustainability/continuous improvement at site scale.
- Strong executive communication/influence across relevant functions and networks.
- Microsoft Office and enterprise systems (Maximo or equivalent CMMS).
Application Instructions:
- Apply now for a career that defies imagination.
As Director, Engineering at Amgen North Carolina (ANC), you will lead the site’s Engineering, Automation, Maintenance, and Instrumentation capabilities to deliver safe, compliant, reliable, and efficient drug-substance manufacturing operations.
Responsibilities:
- Provide strategic and operational leadership for Engineering, Automation, Maintenance, and Instrumentation.
- Ensure safe, reliable, and compliant performance of manufacturing equipment, automation systems, and instrumentation.
- Establish and execute site asset-management strategy (preventive/predictive maintenance, calibration, reliability, spare parts, lifecycle management).
- Lead engineering compliance program (inspection readiness; adherence to cGMP, EHS, quality-system, and regulatory requirements).
- Partner with Site Operations, Quality, Digital/Automation, Supply Chain, and Capital Project Delivery to integrate assets and implement site strategy.
- Lead technical support (system ownership, troubleshooting, root-cause analysis, reliability improvement, corrective actions).
- Establish governance for maintenance execution/work management (planning/scheduling, backlog, work-order quality, contractor oversight, performance metrics).
- Develop/manage/forecast operating and capital budgets; prioritize against safety, quality, supply, reliability, and lifecycle risks.
- Build and lead a high-performing organization; set accountabilities, develop talent, and create succession plans.
- Manage service-provider relationships to ensure safe, compliant, quality work.
- Escalate significant risks with options/recommendations.
- Drive continuous improvement (lean maintenance, digital tools, reliability engineering, sustainability initiatives).
- Represent ANC in global networks; adopt leading practices.
- Make timely, risk-based decisions to protect patients, employees, compliance, and supply.
What We Expect Of You
Basic Qualifications:
- Doctorate + 4 years Engineering experience OR Master’s + 8 years OR Bachelor’s + 10 years.
- At least 4 years directly managing people and/or leadership experience leading teams/projects/programs or allocating resources (may run concurrently).
Preferred Qualifications:
- 12+ years in engineering/maintenance/automation/instrumentation/utilities/reliability/asset-management in pharma/biotech or similarly regulated manufacturing.
- 7+ years leadership (direct management; accountability for multi-function teams, contractors, service providers).
- Site-level E/A/M/I leadership supporting GMP manufacturing.
- Proven reliability/compliance accountability for equipment, automation platforms, instrumentation, clean utilities, and support systems.
- CMMS experience (e.g., Maximo) for maintenance/calibration/reliability/lifecycle/spare parts.
- Experience building technical orgs (workforce strategy, capability development, succession planning, contractor models, vendor governance).
- Track record leading through inspections, quality events, deviations, root-cause investigations, and CAPA.
- Capital project partnership (design/commissioning/qualification/turnover/operational readiness).
- Ownership of operating/capital budgets and cost forecasts/business cases.
- Implementing engineering excellence/reliability/digital/sustainability/continuous improvement at site scale.
- Strong executive communication/influence across relevant functions and networks.
- Microsoft Office and enterprise systems (Maximo or equivalent CMMS).
Application Instructions:
- Apply now for a career that defies imagination.