Clinical Trial Manager
Verastem Oncology
September 03, 2026
Remote friendly (Greater Boston)
United States
Clinical Research and Development
Summary:
We are seeking a Clinical Trial Manager with experience managing a global Phase 3 clinical trial.
Responsibilities:
- Act as primary liaison between clinical vendors (CRO, IRT, eTMF) and Verastem Oncology to ensure expectations, scope of work, quality, and budget; manage changes in SOW and related accruals.
- Manage assigned clinical trials to ensure they are conducted efficiently, on time, within budget, and per SOPs and applicable regulatory requirements.
- Oversee the project lifecycle from set-up through close-out, including vendor performance, internal metrics, quality assurance, and trial status communication.
- Support RFPs for vendor selection; review proposals, coordinate bid defenses, and help maximize savings.
- Negotiate master service agreements, work orders, contracts, and amendments for sites/vendors.
- Assist with study feasibility and participate in site selection.
- Contribute to writing/reviewing clinical documents (protocols, informed consent forms, CRFs and guidelines, and other study documents).
- Coordinate deliverables with medical monitor and cross-functional teams (e.g., safety/medical monitoring/clinical monitoring plans; clinical study reports; pharmacy/lab manuals).
- Partner with Data Management on ongoing data cleaning (metrics, patient profiles, data listings).
- Address issues/risks with CRO/core team and develop mitigation plans.
- Oversee CRO monitoring activities (visit reports, deviations, CAPAs); attend co-monitoring visits as required.
- Chair study team meetings; maintain minutes and action items.
- Meet regularly with Manager to discuss plans, forecasting, and solutions to issues.
- Ensure trial master file set-up and ongoing “audit ready” status.
- Ensure corrective action plans are implemented with QA and vendors/sites; may participate in audits.
- Update tracking spreadsheets; forecast budgets and reconcile actuals with Finance.
- Create/update clinical SOPs with Quality Assurance.
Qualifications:
- Global Phase 3 clinical trial management experience.
- Minimum 3 years clinical trial experience, including oncology studies; BA/BS (or equivalent) in a scientific/health care field.
- Strong knowledge of ICH, GCP, and applicable regulatory guidelines.
- Excellent verbal and written communication.
- Ability to prioritize and multi-task.
- Travel may be required.
Benefits:
- Base salary range: $100K–$125K; eligible for annual bonus, equity compensation, and competitive benefits package.
We are seeking a Clinical Trial Manager with experience managing a global Phase 3 clinical trial.
Responsibilities:
- Act as primary liaison between clinical vendors (CRO, IRT, eTMF) and Verastem Oncology to ensure expectations, scope of work, quality, and budget; manage changes in SOW and related accruals.
- Manage assigned clinical trials to ensure they are conducted efficiently, on time, within budget, and per SOPs and applicable regulatory requirements.
- Oversee the project lifecycle from set-up through close-out, including vendor performance, internal metrics, quality assurance, and trial status communication.
- Support RFPs for vendor selection; review proposals, coordinate bid defenses, and help maximize savings.
- Negotiate master service agreements, work orders, contracts, and amendments for sites/vendors.
- Assist with study feasibility and participate in site selection.
- Contribute to writing/reviewing clinical documents (protocols, informed consent forms, CRFs and guidelines, and other study documents).
- Coordinate deliverables with medical monitor and cross-functional teams (e.g., safety/medical monitoring/clinical monitoring plans; clinical study reports; pharmacy/lab manuals).
- Partner with Data Management on ongoing data cleaning (metrics, patient profiles, data listings).
- Address issues/risks with CRO/core team and develop mitigation plans.
- Oversee CRO monitoring activities (visit reports, deviations, CAPAs); attend co-monitoring visits as required.
- Chair study team meetings; maintain minutes and action items.
- Meet regularly with Manager to discuss plans, forecasting, and solutions to issues.
- Ensure trial master file set-up and ongoing “audit ready” status.
- Ensure corrective action plans are implemented with QA and vendors/sites; may participate in audits.
- Update tracking spreadsheets; forecast budgets and reconcile actuals with Finance.
- Create/update clinical SOPs with Quality Assurance.
Qualifications:
- Global Phase 3 clinical trial management experience.
- Minimum 3 years clinical trial experience, including oncology studies; BA/BS (or equivalent) in a scientific/health care field.
- Strong knowledge of ICH, GCP, and applicable regulatory guidelines.
- Excellent verbal and written communication.
- Ability to prioritize and multi-task.
- Travel may be required.
Benefits:
- Base salary range: $100K–$125K; eligible for annual bonus, equity compensation, and competitive benefits package.