Stoke Therapeutics logo

Associate Scientist, in vivo Pharmacology

Stoke Therapeutics
On-site
Bedford, MA
Clinical Research and Development

Role Summary

The Associate Scientist, in vivo Pharmacology, will join Stoke's In Vivo Pharmacology Department. This role offers opportunities to learn new techniques and concepts, be creative, and grow with a growing company. Based in Bedford, MA.

Responsibilities

  • Design and execute routine studies to investigate the PK/PD and efficacy of drug candidates.
  • Perform routine to intermediate handling procedures and injections, monitor animal health, and collect tissues in mice.
  • Perform moderately complex behavioral experiments in animal models.
  • Support the implementation of new animal models.
  • Demonstrate technical proficiency to investigate, identify, develop, optimize, and troubleshoot new methods/ techniques/ instrumentation to address critical project needs.
  • Read and understand scientific literature.
  • Analyze data, author technical reports, and document experiments in an electronic notebook.
  • Participate and present at project team and departmental meetings.
  • Maintain laboratory organization including equipment upkeep and ensure compliance with safety protocols.
  • Collaborate across functional areas.

Qualifications

  • S with 7+ years post-graduate experience or M.S. with 4+ years of experience working in a biotechnology or pharmaceutical company or contract research organization.
  • Experience working with animal disease models.
  • Experience with animal behavioral assays.
  • Experience with subcutaneous and intravenous injections in rodents; intracerebroventricular injection experience a plus.
  • Experience with molecular biology assays such as PCR, ELISA, MSD, BCA, Western Blot (or JESS).
  • Strong organizational skills and attention to detail.
  • Strong verbal and written communication skills.
  • Creative thinking and working well in a team environment.
  • Experience in neuroscience a plus.
  • Experience with ISH/IHC a plus.

Additional Requirements

  • Travel: This position will require approximately 0% travel.