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Associate Scientist, Bioassay Development

Denali Therapeutics
Full-time
Remote friendly (South San Francisco, CA)
United States
$107,000 - $131,000 USD yearly
Clinical Research and Development

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Role Summary

Associate Scientist, Bioassay Development

Responsibilities

  • Independently perform bioassays to support cell and plate-based (ELISA, ENZYME ACTIVITY) development for late stage molecule
  • Assist in the development, optimization, and qualification of assays for product release and stability testing as well as characterization of biological activity
  • Support study sample testing, analysis and maintain complete and accurate records and contribute to continuing process improvement
  • Evaluate, characterize, and document critical reagents to meet QC standards
  • Coordinate parallel tasks across multiple projects and prioritize deliverables to meet departmental and organizational goals
  • Promote innovation and explore novel analytical techniques or technology

Qualifications

  • BS with 3+ years of industry experience or an MS 1+ years relevant experience in the industry
  • Experience in developing and optimizing bioassays using cell based assay, ELISA, HTRF, Enzyme activity, Enzyme Kinetics, Octet is required
  • Proficient in aseptic technique, mammalian and primary cell handling
  • Proficient in data analysis with Excel and statistical tools such as GraphPad Prism, SoftMax Pro, and PLA 3.0
  • Familiar with electronic notebooks and documentation workflows
  • Ability to balance competing priorities and thrive in a dynamic, fast-paced environment
  • Excellent laboratory, critical thinking, scientific problem-solving, and organizational skills
  • Excellent oral and written communication skills
  • Motivated, detail-oriented, naturally curious individual with a creative approach to scientific problem solving and a burning desire to help patients with neurodegenerative diseases
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