Associate Director, Global Health Economics Lead, Oncology Business Unit

Role Summary

Associate Director, Global Health Economics Lead, Oncology Business Unit.

Responsibilities

• Drive value demonstration strategies for Health Technology Appraisal (HTA; including the EU Joint Clinical Assessment [JCA]) and payer assessments to optimize rapid, broad patient access, achieve value-based prices and lead performance in line with commercial objectives
• Lead health economics (HE) plans and outline strategic approaches to drive pricing and reimbursement activities. Drive hands-on economic assessments for oncology medicines at all stages of development, using HE models and materials including systematic literature reviews (SLRs), indirect treatment comparisons (ITCs), statistical analyses of trial and real-world data and other methods as appropriate
• Oversee country roll-out and training on global HE materials and provide country response to payer inquiries. Lead the development and country adaptations of HTA models with regional and local operating company (LOC) Market Access and HE leads
• Lead and develop robust publication plans to drive access to portfolio medicines through HTA assessments and life cycle management
• Establish a comprehensive understanding of the burden of disease(s), unmet need and appropriate comparator
• Co-lead with Market Access the development of the global value proposition to ensure a compelling value story for payers
• Identify and prioritize strategic opportunities to enhance and expand product value proposition for new indications
• Drive evidence generation planning to optimally provide the product clinical, economic and humanistic value to HTA bodies, payers and market access decision makers and lead the coordination across functions to ensure evidence needs are incorporated into Global, Regional and Local initiatives
• Thoroughly evaluate the anticipated outcome of HTA body assessments and the implications for value positioning and evidence requirements, and shape the product’s evidence generation plan
• Make recommendations to cross-functional business partners about the need for additional data generation – clinical trial, real world evidence (RWE) such as registries and databases – based on evidentiary requirement of payers and HTA bodies
• Lead the integration of payer-relevant HE endpoints in the clinical development plan
• Lead the development of state of the art HE models and studies (e.g., SLRs, ITCs) with sufficient evidentiary support to withstand critique of HTA bodies and other key access decision makers
• Lead training to Regions and LOCs on product value platforms, new evidence and HE studies and models
• Co-lead with Pricing & Market Access the conceptualization of value-based contract (VBC) options, develop VBC toolkits, and assess their commercial impact and effect on cost-effectiveness and budgetary impact
• Support the development/updating and review of the product value platform (including but not limited to Value Story, Global Value Dossiers, Objection Handler, Access Solutions Toolkit and Global Pricing Guidance)
• As the expert on the product’s value proposition and evidence package, proactively address brand-related payer, HTA and policymaker demands and respond to emerging or unforeseen market opportunities/challenges in close coordination with the regional/local PVA Leads
• Maintain awareness of the quickly evolving Global HTA and reimbursement landscape and the evidentiary needs of health care decision-makers to guide HE strategies
• Ensure the drug’s value proposition will be recognized among the external stakeholder community and hence market access and market uptake will be maximized
• Communicate and translate HE messages effectively in manuscripts, posters and publications, and develop appropriate communication materials and tools for payers and population healthcare decision makers
• Foster productive collaboration and effectively manage several important partnerships and consultants, to achieve impact and contribute to the company’s success
• Develop and manage strong collaborations with HE key opinion leaders, academic researchers and vendors to ensure excellence in HE activities and being up to date on the latest and most innovative HE methods
• Lead Role of Takeda Oncology HE projects accountable to Head, Global Health Economics & US HEOR
• Scope to lead and partner with all LOCs globally in value demonstration and HTA via HE modelling and relevant studies (e.g., SLRs, ITCs, RWE)
• Remit includes all in-market brands and development molecules
• Lead and partner with LOCs globally in cross-functional collaborations to achieve impact and align with strategic priorities

Qualifications

• Doctorate with 4+ years of experience, Master's with 6+ years of experience or Bachelor's with 8+ years of experience in healthcare industry with direct experience in global product value proposition development and interaction with payers, HTA bodies, relevant policymakers and strong patient-centered focus
• Robust understanding of the global payer environment and in-depth understanding of ex-US payer landscape including HTA trends and guidance (e.g., NICE, CADTH, PBAC, EU JCA) along with knowledge of US Medicare (Part D), ICER in the US and trends in Emerging Markets (e.g., China) – including reimbursement methodologies, pricing/reimbursement authorities’ decision-making process and current reimbursement issues
• Strong knowledge and hands on experience in health economics, health technology assessment (HTA) tools, methods and filings, SLRs, ITCs, statistical analyses and economic modelling
• Knowledge and understanding of clinical and epidemiological information, innovative global pricing models, all phases of drug development methods of analysis of large databases (e.g., claims data, electronic health records) and the major areas of Outcomes Research (PROs, modelling)
• Leadership – strong ability/desire to work in a highly matrixed organization
• Strong analytical capabilities and excellent communication skills (written and oral)
• Strategic thinking and demonstrated problem solving capability
• Influencing skills (one on one and in group setting) – consensus builder with ability to effective drive decision making
• Ability to translate technical issues to non-technical experts

Preferred

• Previous experience in Hematology and/or Oncology
• A combination of Global and US, in-depth knowledge of HTA (including EU JCA) requirements and direct experience in HTA submissions
• Direct payer experience and/or experience in Market Access
• Track record of peer-reviewed publications

Travel Requirements

• 5 to 10% Domestic and/or International travel may be required