Associate Director, Drug Discovery Toxicology

Role Summary

Associate Director, Drug Discovery Toxicology

Responsibilities

• Represent Toxicology as the Subject Matter Expert on cross-functional project teams within Discovery
• Provide expert input, guidance and strategy on project safety assessments, with a specific focus on discovery projects
• Act as a key resource for early safety assessment during the drug discovery phase, providing scientific knowledge and expertise to cross-functional project teams
• Use established toxicology screening strategies to predict, assess and mitigate target- and drug-related safety risks in support of the drug discovery portfolio
• Refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues
• Collaborate with CROs to ensure best practice for in vitro and/or in vivo safety assessment
• Prepare verbal and written summaries for internal discussions. Work with the Discovery teams to develop optimal strategies to address specific safety issues within the project teams
• Present summary data to project teams, Recursion senior leadership and external partners as needed

Qualifications

• DVM, PharmD, PhD in toxicology, Pathology, Physiology, Biochemistry or related disciplines; emphasis on Oncology/Immunology preferred. Board Certification in Toxicology (DABT/ERT) a plus
• 7+ years experience in safety sciences in the Biotech/Pharma industry
• Experience in project team membership as a toxicology representative in a matrix environment
• Experience with in silico and in vitro safety assessment required; in vivo safety assessment a plus
• In-depth knowledge of discovery toxicology and experience designing and evaluating exploratory toxicology studies
• Secondary pharmacology assessment experience advantageous
• Understanding of in vitro to in vivo translation of toxicities and implications for human safety
• Broad background in novel methods for identifying toxicities and developing risk mitigation plans
• Experience with AI tools to predict toxicology endpoints advantageous
• Highly motivated, independent scientist with excellent oral/written communication skills

Skills

• Clinical and translational toxicology expertise
• Strategic thinking for safety assessment in discovery programs
• Cross-functional collaboration and leadership on project teams
• In vitro and in vivo safety assessment design and interpretation
• Effective scientific communication, verbal and written

Education

• Doctoral or equivalent degree in toxicology, pharmacology, or related field; professional board certification preferred

Additional Requirements

• Location: Office-based, hybrid role in New York City or London; in-office at least 50% of the time
• Relocation support available
• Eligible for annual bonus, equity compensation, and comprehensive benefits