Associate Director, Clinical Portfolio Technology
Alnylam Pharmaceuticals
August 25, 2026
Remote friendly (Cambridge, MA)
United States
IT
Responsibilities:
- Drive delivery, adoption, and continuous improvement of clinical technology capabilities supporting trial execution, study oversight, and portfolio decision-making.
- Partner with stakeholders across Clinical Operations, Study Management, Portfolio Management, and DSSE to translate business priorities into technology plans, roadmaps, and measurable outcomes.
- Support delivery, enhancement, and lifecycle management of platforms enabling trial execution, oversight, portfolio analytics, and data-driven decisions.
- Serve as liaison between Clinical Development and IT, translating needs, risks, priorities, and trade-offs across teams.
- Coordinate with product owners, vendors, and internal IT teams for requirements, scope, dependencies, testing, issue resolution, and release readiness.
- Ensure solutions are compliant, validated, and inspection-ready under GxP expectations (including 21 CFR Part 11, EU Annex 11), with change control, documentation, and quality practices.
- Identify opportunities to simplify processes, improve data flows, reduce manual effort, and enhance user experience.
- Collaborate with Quality, Security, Architecture, Infrastructure, Integration, Analytics, and application teams to ensure secure, scalable, supportable enterprise-aligned solutions.
Qualifications:
Required:
- Bachelor’s degree in IT, Computer Science, Life Sciences, or related; advanced degree preferred.
- 8+ years life sciences technology experience, including regulated clinical development platforms.
- Strong understanding of clinical trial processes/systems and ability to translate operational needs into technology solutions.
- Working knowledge of GxP (21 CFR Part 11, EU Annex 11), validation, change control, and inspection readiness.
- Experience with major life sciences technology vendors and cross-functional regulated delivery.
- Strong communication and stakeholder management.
- Collaboration, sound judgment, learning agility; hands-on problem-solving.
Preferred:
- Experience with Medidata, SAS, R/Posit, Veeva Vault, Elluminate, CTMS, EDC, eCOA, eTMF, RBQM, clinical dashboards, portfolio tools.
- Familiarity with data standards, integrations, analytics/visualization.
- Interest in AI-enabled capabilities applied responsibly.
- Familiarity with Agile and product-oriented delivery; vendor management.
Benefits:
- Annual short-term incentive award and annual long-term incentive award (e.g., equity).
- Comprehensive benefits: medical/dental/vision; life/disability; lifestyle reimbursement; flexible spending/HSAs; 401(k) with company match; paid time off, wellness days, holidays, recharge breaks; family resources and leave.
U.S. Pay Range:
- $172,200.00 - $233,000.00
- Drive delivery, adoption, and continuous improvement of clinical technology capabilities supporting trial execution, study oversight, and portfolio decision-making.
- Partner with stakeholders across Clinical Operations, Study Management, Portfolio Management, and DSSE to translate business priorities into technology plans, roadmaps, and measurable outcomes.
- Support delivery, enhancement, and lifecycle management of platforms enabling trial execution, oversight, portfolio analytics, and data-driven decisions.
- Serve as liaison between Clinical Development and IT, translating needs, risks, priorities, and trade-offs across teams.
- Coordinate with product owners, vendors, and internal IT teams for requirements, scope, dependencies, testing, issue resolution, and release readiness.
- Ensure solutions are compliant, validated, and inspection-ready under GxP expectations (including 21 CFR Part 11, EU Annex 11), with change control, documentation, and quality practices.
- Identify opportunities to simplify processes, improve data flows, reduce manual effort, and enhance user experience.
- Collaborate with Quality, Security, Architecture, Infrastructure, Integration, Analytics, and application teams to ensure secure, scalable, supportable enterprise-aligned solutions.
Qualifications:
Required:
- Bachelor’s degree in IT, Computer Science, Life Sciences, or related; advanced degree preferred.
- 8+ years life sciences technology experience, including regulated clinical development platforms.
- Strong understanding of clinical trial processes/systems and ability to translate operational needs into technology solutions.
- Working knowledge of GxP (21 CFR Part 11, EU Annex 11), validation, change control, and inspection readiness.
- Experience with major life sciences technology vendors and cross-functional regulated delivery.
- Strong communication and stakeholder management.
- Collaboration, sound judgment, learning agility; hands-on problem-solving.
Preferred:
- Experience with Medidata, SAS, R/Posit, Veeva Vault, Elluminate, CTMS, EDC, eCOA, eTMF, RBQM, clinical dashboards, portfolio tools.
- Familiarity with data standards, integrations, analytics/visualization.
- Interest in AI-enabled capabilities applied responsibly.
- Familiarity with Agile and product-oriented delivery; vendor management.
Benefits:
- Annual short-term incentive award and annual long-term incentive award (e.g., equity).
- Comprehensive benefits: medical/dental/vision; life/disability; lifestyle reimbursement; flexible spending/HSAs; 401(k) with company match; paid time off, wellness days, holidays, recharge breaks; family resources and leave.
U.S. Pay Range:
- $172,200.00 - $233,000.00