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Associate Director, Accounting

Denali Therapeutics
August 29, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Corporate Functions
Role: Lead accounting operations for a biotech company's finance team, focusing on financial close, internal controls, and systems governance to ensure accurate reporting and compliance. Responsibilities: oversee monthly, quarterly, and annual close processes; manage accounting for R&D expenses, stock-based compensation, and payroll-related activities; serve as process owner for SOX controls, collaborate with external auditors, and lead system enhancements (Coupa, SAP). Provide leadership and development for the accounting team, drive process improvements, and support external audits and SEC reporting. Qualifications: active CPA, Bachelor's in Accounting or Finance, 9+ years of industry experience with 5+ years in management, including Big Four public accounting (~5+ years). Expertise in U.S. GAAP, SOX, public company reporting, and biotech/pharma industry experience required; system proficiency in SAP and Coupa preferred. HighValue: biotechnology, clinical trial expense accounting, SOX compliance, public company reporting, SAP and Coupa platforms, team leadership. WorkSetup: not specified; likely hybrid or onsite given seniority and collaboration needs.