Analytics CoE Senior Manager
Vertex Pharmaceuticals
August 19, 2026
Remote friendly (Boston, MA)
United States
IT
Key Responsibilities:
- Leverage Vertex’s in-licensed RWE data assets to conduct queries and analyses supporting the Vertex product portfolio and development programs across therapeutic and disease areas.
- Conduct feasibility assessments to inform design/execution of research projects.
- Conduct health economic and outcomes research to characterize disease burden, healthcare resource utilization, co-morbidities, and treatment patterns in real-world populations.
- Generate actionable insights to address key business questions from internal and external stakeholders.
- Lead development of study protocols, statistical analysis plans, and table shells.
- Support statistical programmers by executing data queries and analyses.
- Generate analytic reports, tables, and visualizations to communicate findings to internal stakeholders.
- Collaborate with cross-functional colleagues to improve the analytics operating model.
- Develop/enhance/maintain internal analytic tools (e.g., programming libraries, reusable macros, table templates).
- Support HEOR disease/asset leads in assessing research gaps and evidence generation objectives.
Qualifications:
- Advanced degree in health economics or related discipline (math, statistics, economics, epidemiology).
- Typically 6 years of relevant experience in health economics and outcomes research (or equivalent: Doctorate + 2 years; Master’s + 4 years).
- Knowledge of observational research methods for studies of disease burden, resource utilization, treatment patterns, comorbidities, and outcomes.
- Hands-on experience analyzing large patient-level healthcare datasets (open/closed claims, EHR/EMR, hospital chargemaster; e.g., MarketScan, PharMetrics Plus, eLAAD+, Premier).
- Working knowledge of national healthcare coding systems (diagnostic, procedure, drug) and healthcare system structures.
- Advanced proficiency in SAS programming and Excel required.
- Excellent written and oral communication skills.
- Ability to plan, organize, and manage multiple projects across therapeutic areas.
- Leverage Vertex’s in-licensed RWE data assets to conduct queries and analyses supporting the Vertex product portfolio and development programs across therapeutic and disease areas.
- Conduct feasibility assessments to inform design/execution of research projects.
- Conduct health economic and outcomes research to characterize disease burden, healthcare resource utilization, co-morbidities, and treatment patterns in real-world populations.
- Generate actionable insights to address key business questions from internal and external stakeholders.
- Lead development of study protocols, statistical analysis plans, and table shells.
- Support statistical programmers by executing data queries and analyses.
- Generate analytic reports, tables, and visualizations to communicate findings to internal stakeholders.
- Collaborate with cross-functional colleagues to improve the analytics operating model.
- Develop/enhance/maintain internal analytic tools (e.g., programming libraries, reusable macros, table templates).
- Support HEOR disease/asset leads in assessing research gaps and evidence generation objectives.
Qualifications:
- Advanced degree in health economics or related discipline (math, statistics, economics, epidemiology).
- Typically 6 years of relevant experience in health economics and outcomes research (or equivalent: Doctorate + 2 years; Master’s + 4 years).
- Knowledge of observational research methods for studies of disease burden, resource utilization, treatment patterns, comorbidities, and outcomes.
- Hands-on experience analyzing large patient-level healthcare datasets (open/closed claims, EHR/EMR, hospital chargemaster; e.g., MarketScan, PharMetrics Plus, eLAAD+, Premier).
- Working knowledge of national healthcare coding systems (diagnostic, procedure, drug) and healthcare system structures.
- Advanced proficiency in SAS programming and Excel required.
- Excellent written and oral communication skills.
- Ability to plan, organize, and manage multiple projects across therapeutic areas.