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Analyst II, Information Security (Operational Technology)

Arrowhead Pharmaceuticals
September 18, 2026
Full-time
Remote friendly (San Diego, CA)
Worldwide
IT
Role: Information Security Analyst II focused on safeguarding Operational Technology and Information Technology environments within a biopharma manufacturing setting. Objectives: ensure security, compliance, and reliability of production and enterprise systems supporting pharmaceutical manufacturing processes. Responsibilities: support cybersecurity initiatives for ICS, MES, DCS, SCADA, PLC, and related operational systems; assist with asset inventories, vulnerability management, risk assessments, and remediation; collaborate with Engineering and Manufacturing to implement security controls; monitor threats affecting industrial control environments; develop security policies, manage endpoint security, conduct risk analyses, and support incident response. Requirements: Bachelor's degree in Information Security, IT, or related field; 3+ years in OT/security roles supporting manufacturing environments; knowledge of Purdue architecture, ISA/IEC standards, NIST frameworks, and security best practices; experience with system hardening, vulnerability management, and enterprise networking. Preferred: cybersecurity experience in OT/ICS environments; familiarity with OT security platforms like Dragos, Claroty, Nozomi; relevant certifications; hands-on with OT detection tools; knowledge of industrial networking, historians, batch systems, and regulatory inspections. High-Value: manufacturing security, OT/ICS, pharma production systems, risk management, threat mitigation, compliance standards. WorkSetup: Not specified; likely hybrid or on-site, with salary ranges from $80K–$110K depending on location.