Vice President, Translational Medicine

Role Summary

Vice President of Translational Medicine to lead integration of clinical data across early development programs, synthesizing diverse datasets into a coherent framework that informs clinical strategy and decision-making. Primary focus on dose selection, trial design, and regulatory success, with active data engagement and cross-functional collaboration.

Responsibilities

• Strategic Integration & Decision Support
• Lead the hands-on integration of clinical data across modalities and endpoints to inform program strategy.
• Develop and communicate a data-driven narrative that connects mechanistic understanding with clinical outcomes.
• Translate complex datasets into clear recommendations for dose selection, trial design, and go/no-go decisions.
• Ensure translational insights are embedded in clinical protocols, regulatory filings, and development milestones.
• Cross-Functional Leadership
• Partner with medical leads, clinical science, clinical operations, biomarker, regulatory, and safety teams to align translational strategy with program goals.
• Serve as a key contributor to governance and program teams, representing translational science in strategic discussions.
• Collaborate with external experts and CROs to support modeling, PK analysis, and specialized translational efforts.
• Team Building & Mentorship
• Lead and mentor a growing translational team, fostering a culture of scientific excellence and strategic thinking.
• Define and evolve the function‚Äôs capabilities, including biomarker strategy, clinical pharmacology, and data integration.
• Identify and manage external partnerships to complement internal expertise.
• Regulatory & Scientific Engagement
• Support regulatory interactions by providing integrated translational insights and data interpretation.
• Represent the company in scientific forums, advisory boards, and external collaborations.

Qualifications

• PhD, PharmD, or MD in pharmacology, immunology, translational science, or a related field.
• 12+ years of experience in translational medicine, clinical development, or related areas in biotech/pharma.
• Demonstrated ability to integrate and interpret complex clinical datasets into strategic program decisions from early clinical development to late-stage clinical trials.
• Strong understanding of PK/PD principles, biomarker development, and regulatory expectations.
• Experience with biologics, ADCs, or immunotherapies is highly desirable. Direct experience within oncology and autoimmune will be given priority.
• Exceptional communication skills, with the ability to translate science into strategy and influence cross-functional teams.
• Strong track record of contributing to regulatory submissions and engaging with global health authorities.
• Strong organizational and time management abilities.
• High level of accountability, adaptability, and attention to detail.
• Ability to work independently and collaboratively in a fast-paced, matrixed environment.
• Ability to travel up to 15%