Vice President, Toxicology
Alnylam Pharmaceuticals
6 hours ago
Remote friendly (Greater Boston)
United States
$284,800 - $385,200 USD yearly
Clinical Research and Development
Responsibilities:
- Lead and oversee a team of toxicologists and technical staff, fostering scientific excellence, collaboration, and professional development.
- Provide strategic leadership for nonclinical safety assessment programs supporting discovery, development, and regulatory submissions.
- Collaborate across disciplines (pathology, DMPK, biology, clinical, regulatory, and pharmacology) to ensure strong cross-functional integration.
- Engage with regulatory authorities, supporting product defense and contributing to regulatory submissions and approvals.
- Design and implement scientifically robust, strategically aligned nonclinical development programs to support drug candidate advancement and regulatory filings.
- Lead and manage nonclinical studies and programs across a portfolio of projects, internally and through CRO partners, either directly or via direct reports.
- Prepare and critically review scientific and regulatory documents for quality, clarity, and sound scientific interpretation.
- Partner with cross-functional teams to design investigative toxicology studies supporting development candidates and platform technology evaluations.
- Present key findings and safety strategies to program teams, R&D leadership, and regulatory authorities.
- Mentor and develop toxicologists and scientists to build organizational expertise in pharmaceutical toxicology and nonclinical safety.
Qualifications:
- PhD in Toxicology, Pathology, or a related scientific discipline.
- 15+ years of experience in the pharmaceutical or biotechnology industry, with demonstrated expertise and accomplishments in regulatory toxicology.
- Proven leadership experience managing departments, groups, or teams within a scientific organization.
- Demonstrated experience preparing and supporting global regulatory submissions and associated documentation.
- Strong ability to interpret and integrate complex datasets across pharmacology, DMPK, toxicology, and pathology, assessing clinical relevance and impact.
- Proven ability to apply creative and strategic approaches to resolving challenges in predictive toxicology.
- Strong problem-solving skills and ability to remain highly organized in a fast-paced, changing-priority environment.
- Excellent interpersonal skills and ability to collaborate across diverse cross-functional teams.
- Excellent written and verbal communication skills.
- Strong interest in therapeutic and scientific areas aligned with Alnylam’s research focus.
Benefits:
- Base salary range: $284,800.00 - $385,200.00
- Eligible for annual short-term incentive award and annual long-term incentive award (e.g., bonus or equity).
- Comprehensive medical, dental, and vision coverage; life and disability insurance; lifestyle reimbursement program; flexible spending and health savings accounts; 401(k) with company match; paid time off; wellness days; holidays; and two company-wide recharge breaks.
Application instructions:
- Learn more about additional benefits: https://www.alnylam.com/careers
- Lead and oversee a team of toxicologists and technical staff, fostering scientific excellence, collaboration, and professional development.
- Provide strategic leadership for nonclinical safety assessment programs supporting discovery, development, and regulatory submissions.
- Collaborate across disciplines (pathology, DMPK, biology, clinical, regulatory, and pharmacology) to ensure strong cross-functional integration.
- Engage with regulatory authorities, supporting product defense and contributing to regulatory submissions and approvals.
- Design and implement scientifically robust, strategically aligned nonclinical development programs to support drug candidate advancement and regulatory filings.
- Lead and manage nonclinical studies and programs across a portfolio of projects, internally and through CRO partners, either directly or via direct reports.
- Prepare and critically review scientific and regulatory documents for quality, clarity, and sound scientific interpretation.
- Partner with cross-functional teams to design investigative toxicology studies supporting development candidates and platform technology evaluations.
- Present key findings and safety strategies to program teams, R&D leadership, and regulatory authorities.
- Mentor and develop toxicologists and scientists to build organizational expertise in pharmaceutical toxicology and nonclinical safety.
Qualifications:
- PhD in Toxicology, Pathology, or a related scientific discipline.
- 15+ years of experience in the pharmaceutical or biotechnology industry, with demonstrated expertise and accomplishments in regulatory toxicology.
- Proven leadership experience managing departments, groups, or teams within a scientific organization.
- Demonstrated experience preparing and supporting global regulatory submissions and associated documentation.
- Strong ability to interpret and integrate complex datasets across pharmacology, DMPK, toxicology, and pathology, assessing clinical relevance and impact.
- Proven ability to apply creative and strategic approaches to resolving challenges in predictive toxicology.
- Strong problem-solving skills and ability to remain highly organized in a fast-paced, changing-priority environment.
- Excellent interpersonal skills and ability to collaborate across diverse cross-functional teams.
- Excellent written and verbal communication skills.
- Strong interest in therapeutic and scientific areas aligned with Alnylam’s research focus.
Benefits:
- Base salary range: $284,800.00 - $385,200.00
- Eligible for annual short-term incentive award and annual long-term incentive award (e.g., bonus or equity).
- Comprehensive medical, dental, and vision coverage; life and disability insurance; lifestyle reimbursement program; flexible spending and health savings accounts; 401(k) with company match; paid time off; wellness days; holidays; and two company-wide recharge breaks.
Application instructions:
- Learn more about additional benefits: https://www.alnylam.com/careers