Vice President, Early Discovery Chemistry

Role: Vice President of Early Discovery Chemistry, leading multidisciplinary teams to discover novel chemical matter for oncology drug development. Objectives include defining strategies for targeting challenging oncology proteins, integrating innovative chemistry, computational design, AI/ML, automation, and screening technologies to accelerate hit identification and expand chemical space. Responsibilities encompass fostering innovation, managing a high-performing team, and collaborating across research functions to facilitate seamless transition from discovery to lead optimization. Requirements: Ph.D. in Organic or Medicinal Chemistry, 15+ years in industrial drug discovery with leadership in Early Discovery or Medicinal Chemistry, proven success in target-to-lead programs, expertise in library design, screening, and computational chemistry, and strong strategic leadership skills. Preferred: experience with challenging oncology targets, covalent inhibitors, molecular glues, targeted protein degradation, or ADC payload discovery; external collaboration experience; a record of scientific publications and patents. High-value: focus on oncology, early discovery stage, high innovation, and leadership in chemical sciences within a fast-paced, high-growth biopharma environment. Work setup: not explicitly stated, but likely based at Redwood City, CA, with the potential for remote or hybrid arrangements based on company policy.