Vice President, Business Operations & Partnerships

Key Responsibilities
- Performance & Governance: Enable Pipeline Delivery to make informed, timely decisions through strong governance structures and performance frameworks.
- Design and operationalize governance frameworks across the portfolio (cross-functional trial teams, Pipeline Delivery governance, escalation pathways).
- Define roles, decision rights, and “decision-ready” materials to improve decision clarity and speed.
- Lead function performance tracking (milestones, risks, delivery confidence).
- Provide actionable insights to support prioritization and trade-off decisions.
- Resource Planning & Management:
- Design and implement resource planning frameworks to provide visibility into capacity, demand, and capability needs.
- Partner with Finance and functional leaders to align portfolio strategy, budgets, and resource allocation.
- Optimize internal staffing models and external partner utilization via tools and processes.
- Ensure the organization has the right capabilities and capacity for the evolving pipeline.
- Provide scenario planning and forecasting insights to support strategic decisions.
- Vendor & Alliance Management:
- Define and execute a centralized, forward-looking vendor strategy with governance and accountability.
- Provide strategic oversight and performance management of external partners (including CROs).
- Drive vendor governance and mechanisms to ensure high-quality, cost-effective delivery.
- Ensure partner performance aligns to timelines and priorities; focus on value realization and risk mitigation.
- Leadership Responsibilities:
- Build and lead a high-performing Portfolio Management organization.
- Foster partnerships across Clinical Research, Program Management, Clinical Operations, Data Management, IT, Finance, and external partners.
- Advise senior leaders on operating model design, systems strategy, and execution effectiveness.
- Champion collaboration, transparency, accountability, and innovation; develop scalable organizational capabilities.

Qualifications
- Bachelor’s degree with 20+ years of biotech/pharma experience, expert in Clinical Development Operations.
- Proven ability to design governance models, decision frameworks, escalation pathways, and portfolio performance management processes.
- Demonstrated success in organizational transformation and operating model design/implementation.
- Ability to translate portfolio strategy into actionable plans balancing timelines, budgets, capabilities, and priorities.
- Significant experience managing CROs and external service providers (vendor governance, performance management, contract oversight).
- Strong financial/business acumen (forecasting, budgeting, investment planning, scenario modeling) with Finance partnership.
- Experience creating executive insights, dashboards, and performance metrics.
- Exceptional leadership, collaboration, and influencing in highly matrixed senior environments.
- Strong strategic thinking and problem-solving; anticipate risks and drive operational excellence.
- Excellent communication and executive presence; synthesize complex information into clear recommendations.
- Ability to lead organizational change, build scalable operating models, and drive continuous improvement.
- Prior experience in RNAi or complex, multi-asset pipelines preferred.