Translational Science Associate Director Immunology Cell Therapy

Role Summary

Translational Science Associate Director Immunology Cell Therapy tasked with implementing translational and biomarker objectives for cellular therapies in immune-mediated diseases, leading translational studies, and collaborating across research, development, and CROs to support clinical programs.

Responsibilities

• Implement translational and biomarker objectives for cellular therapies in immune-mediated diseases.
• Foster effective collaborations between research and development; establish target-to-disease connections; differentiate AZ cellular therapeutics.
• Drive translational understanding of clinical trial data and lead translational studies and deliverables with CROs and collaborators.
• Support new and ongoing clinical studies and enable LCM strategy and new program strategies as a GPT-level translational lead.
• Serve as an authority in translational science, addressing difficult drug projects and complex scientific problems with innovative solutions.

Qualifications

• PhD or MD-PhD required; Immunology training preferred.
• 5 years of industry experience with at least 3 years in clinical development or translational science (industry or combined with academia).
• Strong understanding of immune-mediated disease pathogenesis and application of cellular/molecular technologies to drive program decisions.
• Experience in clinical biomarker development for T-cell therapy or other advanced modalities, in-house or with CROs.
• Experience in BM, precision medicine, and IND filings.
• Ability to learn rapidly; proven track record leading CROs for translational studies and biomarkers for clinical trials.
• Authoring experience for regulatory documents; understanding of the full drug development process.
• Knowledge of translational/clinical research methodology and biostatistics; familiarity with FDA/EMA/MHRA/ICH GCP guidelines.
• Experience beyond Phase 1 preferred; detail-oriented with strong communication and strategic planning skills.
• Proven ability to deliver results and lead complex projects; outstanding verbal and written communication.

Skills

• Translational science leadership
• Biomarker development for cellular therapies
• Clinical development coordination with CROs
• Regulatory documentation and IND experience
• Strategic planning and problem solving
• Strong communication and collaboration across multidisciplinary teams

Education

• PhD or MD-PhD in Immunology or related field

Additional Requirements

• In-person collaboration preference with an emphasis on office presence; flexibility supported.