Translational Science Associate Director Immunology Cell Therapy

Role Summary

Translational Science Associate Director Immunology Cell Therapy

Responsibilities

• Implement translational and biomarker objectives for cellular therapies for immune-mediated diseases.
• Establish effective collaborations between research and development; differentiate AZ cellular therapeutics; drive translational understanding of clinical trial data.
• Lead all aspects of translational studies and deliverables with CROs and collaborators to support new and ongoing clinical studies; enable LCM strategy and new program strategies as a GPT level translational lead.
• Act as an authority in translational science, addressing difficult drug projects and complex scientific problems with innovative solutions.

Qualifications

• PhD or MD-PhD required; degree or training in Immunology preferred.
• 5 years of industry experience with 3+ years in clinical development or translational science (industry or combined academic/industry).
• Strong understanding of immune-mediated disease pathogenesis and application of cellular/molecular technologies to drive program decisions.
• Experience in clinical biomarker development of T-cell therapy and/or other advanced modalities (in-house or with CROs).
• Experience in BM, precision medicine, and IND filings.
• Ability to learn new information rapidly; experience leading CROs for translational studies and biomarkers for clinical trials.
• Experience authoring regulatory documents; understanding of full drug development process.
• Strong biostatistics and translational/clinical research methodology knowledge; familiarity with FDA, EMA, MHRA and ICH GCP guidelines.
• Experience beyond Phase 1 preferred.
• Attention to detail, quality-focused work ethic, and urgency to achieve goals; proven track record delivering results.
• Excellent verbal and written communication; strong analytical, problem-solving, and strategic planning skills.

Skills

• Translational science leadership
• Biomarker development
• Clinical development strategy
• Regulatory documentation
• Collaboration with CROs and cross-functional teams
• Biostatistics and data interpretation

Education

• PhD or MD-PhD; Immunology training preferred.

Additional Requirements

• In-person/office-based collaboration pattern; emphasis on leadership and stakeholder engagement.