Supply Chain Manager, Planning & Capacity

Role Summary

Lead strategy and capacity planning for the Amgen North Carolina Drug Substance site (ANC) as part of the Supply Chain team. Provide internal strategic consulting and capacity expertise to help ANC achieve its potential within the Amgen network, delivering accurate and forward-looking capacity visibility to support Master Production Scheduling, Long Range Strategy, New Product Introductions, and commercial supply reliability. Location: Holly Springs, North Carolina.

Responsibilities

• Support business strategy assessment of multiple production plan scenarios to determine options, resource / capital requirements, risk and mitigation strategy, financial and supply implications with support of a cross-functional stakeholder team. Develop metrics and analytics tools to rapidly assess impact of pending changes for assessment.
• Lead end-to-end DS capacity modeling for the ANC site; develop and maintain capacity models incorporating available days, maintenance, run rate, float, success rate, and yield assumptions.
• Identify manufacturing bottlenecks and quantify impact to supply and service levels.
• Ensure ANC DS planning assumptions align with network standards for Available Days, Run Rate, Success Rate, and Yield.
• Maintain accurate planning parameters within Rapid Response and SAP planning systems.
• Develop scenario analyses to support LRS volume expansion, NPIs, capital investments, and risk mitigation strategies.
• Support governance forums tied to LRS and MPS cycles.
• Provide executive-ready summaries to support site and network decision-making.
• Partner cross-functionally with Manufacturing, Engineering, Process Development, and Capital Projects to validate capacity assumptions.
• Support ramp-up planning for new products and assets, transitioning assumptions to demonstrated performance.
• Monitor success rate, run rate, and yield performance against targets and support continuous improvement initiatives.
• Develop dashboards and visualization tools to enhance transparency and executive decision-making.
• Build playbook and templates to ensure documented and easy to follow processes for role successors.

Qualifications

• Required: High school diploma / GED with 10 years of GMP Supply Chain / Manufacturing Planning experience OR Associate’s degree with 8 years of GMP Supply Chain / Manufacturing Planning experience OR Bachelor’s degree with 4 years of GMP Supply Chain / Manufacturing Planning experience OR Master’s degree with 2 years of GMP Supply Chain / Manufacturing Planning experience OR Doctorate degree.
• Preferred: In-depth understanding of biopharmaceutical manufacturing operations
• Preferred: Experience with regulated environments (i.e., cGMP, GDP, OSHA)
• Preferred: Strong understanding of upstream/downstream capacity modeling and bottleneck analysis
• Preferred: Knowledge of yield modeling, run rate, float, and success rate assumptions
• Preferred: Experience supporting LRS and MPS Planning Cycles
• Preferred: Strong technical and data analytic skills and proficiency with AI, Databricks, Excel, SQL, Power BI and Tableau
• Preferred: Supply Chain, Manufacturing Planning and/or Industrial engineering educational background
• Preferred: Experience working with planning systems such as Rapid Response and SAP
• Preferred: Operational Excellence and continuous improvement experience in regulated industry
• Preferred: Good knowledge of Word, Excel, Smartsheet, Miro, and ability to work easily with new software
• Preferred: Strong analytical, problem-solving, and cross-functional collaboration skills
• Preferred: Ability to translate complex manufacturing data into strategic insights
• Preferred: Excellent organizational, communication, and interpersonal skills
• Preferred: Financial and business acumen