Summer 2026 - Graduate/PhD Mechanistic Modeling Internship
Bristol Myers Squibb
Full-time
Remote friendly (Brisbane, CA)
United States
Clinical Research and Development
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Role Summary
Summer 2026 - Graduate/PhD Mechanistic Modeling Internship. Intern will work in the BMS Clinical Pharmacology & Pharmacometrics Department, focusing on mechanistic modeling projects (PMx, QSP, MBMA, PBPK) under the guidance of a scientist. Potential projects include development and testing of mechanistic models, PK/PD modeling, MBMA, and data analysis to support discovery, toxicology, and clinical efforts. Internship runs June–August 2026 across multiple locations (Lawrenceville, NJ; Cambridge, MA; Brisbane, CA).
Responsibilities
- Work with an experienced mentor on a project related to population pharmacokinetic modeling, exposure–response modeling, pharmacokinetic–pharmacodynamic modeling, machine learning in pharmacometrics, and development/parameterization of mechanistic models using systems of ordinary differential equations.
- Present analysis results, typically as a scientific poster or at team meetings.
- Calibrate parametrized mini-models using in-house or public-domain data; identify sensitive parameters; incorporate pathway knowledge into platforms and test against existing therapies.
- Assist in the analysis of discovery, toxicology, and clinical data.
Qualifications
- Enrollment in a graduate program (Ph.D., M.S., PharmD) or undergraduate program where applicable; graduation date expected after August 2026.
- Familiarity with quantitative methods; hands-on experience or coursework with modeling tools such as NONMEM, Monolix, Phoenix/NLME, R, SAS, Python, Simcyp, GastroPlus, or MATLAB/SimBiology.
- Excellent oral and written communication skills and strong problem-solving abilities.
- Authorized to work in the US for the duration of the internship; no visa sponsorship available.
Skills
- Quantitative modeling and data analysis
- Pharmacokinetic and pharmacodynamic modeling
- Mechanistic modeling (ODE-based)
- Data visualization and presenting results
Education
- Relevant fields: Pharmaceutical Sciences/Pharmacy, Engineering, Bioinformatics, Biomedical Sciences, Data Sciences, Mathematics, Statistics.
Additional Requirements
- None beyond the qualifications listed; role is temporary during internship period June–August 2026.