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Study Physician, Medical Director – Neuroimmunology, Immunology, BioPharmaceuticals R&D

AstraZeneca
September 19, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Study Physician, Neuroimmunology, providing clinical and scientific leadership for cell-therapy and immunotherapy programs targeting multiple sclerosis and immune-mediated neurological diseases. Responsibilities include designing, executing, and interpreting early to late-phase clinical trials, assessing safety and efficacy data, and ensuring GCP compliance. The role involves acting as the clinical authority for safety evaluations, managing complex clinical cases, and contributing to development strategies across the neuroimmunology portfolio. Collaboration spans internal cross-functional teams—research, clinical pharmacology, regulatory, CMC, safety—and external stakeholders like investigators, regulators, and patient groups. Qualifications include an MD (or equivalent) with subspecialty training in neurology or immunology, a minimum of 2 years industry clinical development experience, and strong knowledge of GxP guidelines and global regulatory standards. Experience in cell therapy, T-cell engagers, or autoimmune indications is desirable, along with familiarity with operational constraints of cell therapies. The position requires excellent communication, problem-solving skills, and the ability to work effectively in a fast-paced, collaborative environment. Travel expectations are present for national and international engagement. The role is based in a hybrid setup with in-office and remote work options.