Sr. Scientist, Peptide / Bio-organic Chemistry

Who We Are

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About The Role

Seeking a highly motivated and talented peptide chemist to join our discovery Peptide and Bioconjugation research group. The successful candidate will work on the design, synthesis and characterization of novel peptides to discover next-generation peptide-based therapeutics. Your expert synthetic knowledge and proven design and synthetic accomplishments will enable you to have significant impact on Neurocrine’s projects. This is an exciting position to help discover peptide therapeutics of the future.

Your Contributions (include, But Are Not Limited To)

• Lead projects and teams towards agreed upon goals, ultimately working towards clinical candidate peptide nomination
• Synthesis, purification and characterization of peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, purification, analytical and biophysical techniques
• Contributes to project teams towards agreed upon goals, ultimately working towards candidate peptide nomination
• Independent data-driven optimization of peptide SAR
• Effective communication of scientific rationale, results and interpretation at project, team and departmental meetings
• Active collaboration and sharing of expertise with colleagues

Requirements

• BS/BA degree in chemistry or closely related field and 5+ years of experience OR
• MS/MA degree in chemistry or closely related field and 3+ years of similar experience OR
• PhD in chemistry or related field and 2+ years of similar experience
• Proficient in all aspects of modern peptide synthesis, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry
• Strong publication record of accomplishment
• Strong understanding of peptide structure and associated biophysical techniques to assess peptide structure, stability and behavior in solution
• Experience in protein-peptide bioconjugation and purification a plus
• Excellent interpersonal skills with strong oral and written communication abilities
• Assimilates data and research findings outside of Neurocrine for application to new scientific projects
• Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools
• Excellent computer, communications, problem-solving, and analytical thinking skills
• Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

The annual base salary we reasonably expect to pay is $108,600.00-$157,350.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.